Accommodation in Otay Mesa West from AU$210
More than just hotels
Apartments, cabins, holiday rentals and more, plus millions of reviews from Aussie & Kiwi travellers
Flexibility matters
24/7 support, so you can book with confidence
Unlock member prices with Mates Rates
You could save 10% or more on over 100,000 hotels right now.
Check hotel availability in Otay Mesa West
Best Hotels in Otay Mesa West

Hilton San Diego Bayfront

Marriott Marquis San Diego Marina

Manchester Grand Hyatt San Diego

Embassy Suites by Hilton San Diego Bay Downtown

The Dextro Hotel, BW Premier Collection

Wyndham San Diego Bayside

Bay Club Hotel & Marina

Sheraton Mission Valley San Diego Hotel

Handlery Hotel

Hampton Inn San Diego/Mission Valley

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

The Dana on Mission Bay
Hotels In Otay Mesa West
Are you heading to San Diego? You should stop by and reach the Otay Mesa West neighbourhood, located 18 kilometres southeast of the town centre.
San Diego is where you'll find an impressive number of iconic things to see, such as the San Diego Zoo, Seaworld and the San Diego State University.
Stopping in at Fruit Barr Caffe is a great way to kick off your day in Otay Mesa West. Just follow the scent of roasted coffee beans! Unfortunately, our bodies can't run on caffeine alone. Check out the menu at Little Caesars Pizza when your stomach starts to growl. Before strolling back to the hotel, why not pull up a stool at Over the Border for a nightcap? Whether you're a beer or wine drinker, you'll be well looked after here.
Accommodation options near Otay Mesa West
Booking a place to stay in Otay Mesa West's centre could be difficult if you're after a last-minute option, but you'll surely be safe knowing alternatives are available in the San Ysidro hotels guide and in the Wotif Chula Vista hotels guide. San Ysidro is home to the Rodeway Inn and Quality Inn & Suites Near The Border, while in Chula Vista you can check out the Holiday Inn Express San Diego South - Chula Vista and La Quinta Inn San Diego Chula Vista.Otay Mesa West features some fabulous places to stay. So, when you're ready to explore the delights of San Diego, let Wotif take you there!
Otay Mesa West hotels essential information
Accommodation | 6,572 hotels |
---|---|
Lowest Price | AU$210 |
Highest Price | AU$459 |
Popular hotels | Handlery Hotel, Wyndham San Diego Bayside, Embassy Suites by Hilton San Diego Bay Downtown, Manchester Grand Hyatt San Diego, The Dana on Mission Bay, Marriott Marquis San Diego Marina, Hilton San Diego Bayfront, The Dextro Hotel, BW Premier Collection, Hampton Inn San Diego/Mission Valley, Best Western Inn & Suites San Diego – Zoo/SeaWorld Area , Bay Club Hotel & Marina, Sheraton Mission Valley San Diego Hotel |
New reviews! Best hotels in Otay Mesa West

Neighbourhoods
Near an Attraction
More accommodations in Otay Mesa West
Hotels near an airport
Top hotels
More destinations for you
- Hotels in Stanford
- Hotels in Palm Cove
- Hotels in North Beach
- Hotels in Palm Beach
- Hotels in Westwood
- Hotels in Hollywood
- Hotels in Silver Lake
- Apartment Hotels in Hollywood
- Hotels in Marina District
- Byron Bay Accommodation
- Hotels in Fisherman's Wharf
- Lakes Entrance Accommodation
- Melbourne Accommodation
- Hotels in Downtown San Diego
- Hotels with Balconies in Gaslamp Quarter
- Hotels in Union Square
- Rydges Hotels in Melbourne
- Apartment Hotels in Union Square
- Apartment Hotels in Melbourne
- Hotels in Downtown San Francisco
- Makati Accommodation
- Oaks Melbourne on Collins Suites
- Hotels in Gaslamp Quarter
- Gundagai Accommodation
- Hotels in Downtown Los Angeles
- Hotels with Balconies in Downtown Los Angeles
- Hotels in Nob Hill