La Mesa Holiday Packages

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Let us bundle your hotels and flights into a tidy little package.

With the extra money you can experience more in La Mesa.

How does a spare sound? That's exactly how much you could save if you book today. And remember — you can pick and choose from more than 550 airlines and 665,000 worldwide properties.

Wotif boasts some of the most competitive prices anywhere. Better start packing — now's the perfect time for a new adventure.

La Mesa Accommodation

Our database lists 34 accommodations in La Mesa. However, none of them are located directly in the centre. Have a look through your options on Wotif — you're sure to find a great place not too far away.

Searching for somewhere to sleep? No worries — we've got it covered. The Vineyard Hacienda (12685 Campo Rd) and the Holiday Inn Express San Diego South - National City (1645 E Plaza Blvd) both have top reviews and a convenient location.

Car Hire in La Mesa

If you don't have even a minute to lose, the smartest option is to rent a car directly from San Diego International Airport. Economy Rent a car is located near the arrivals area.

There's no need to stress out over hire cars here. Enterprise (8363 Centre Drive, Suite 6H) is our hot tip for this area and is only 2 kilometres from the middle of town.

Holidays to La Mesa

Got a thing for going places you've never visited before? Likewise. But there's no need to get lost in the process. Have a snoop through our guide to La Mesa and you'll be sauntering around like a real local in no time.

The San Diego County neighbourhood of La Mesa sits 16 kilometres from all the excitement of the centre. You'll discover it in the city's east.

If curiosity's your middle name, you'll probably want to learn a few bits of trivia about San Diego County — like how many people call it their home. Well, at last count the population was 1 300 000.

Top La Mesa hotels

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4 out of 5
207 5th Ave San Diego CA
Fully refundableReserve now, pay when you stay
The price is AU$895 per night from 3 Mar to 4 Mar
AU$895
3 Mar - 4 Mar
includes taxes & fees
Hard Rock Hotel San Diego: Hotel with free WiFi and an outdoor pool. Located near a metro station.
Room was very clean and luxurious

Reviewed on 5 Feb 2026

Opens in a new windowHard Rock Hotel San Diego
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

3 out of 5
1617 1st Avenue San Diego CA
Fully refundableReserve now, pay when you stay
The price is AU$190 per night from 22 Feb to 23 Feb
AU$190
22 Feb - 23 Feb
includes taxes & fees
The DEXTRO Little Italy, BW Premier Collection: Business-friendly hotel with free WiFi and an outdoor pool. Located near a train station.
Staff were incredibly friendly and supportive

Reviewed on 8 Feb 2026

Opens in a new windowThe DEXTRO Little Italy, BW Premier Collection
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
Fully refundableReserve now, pay when you stay
The price is AU$328 per night from 1 Mar to 2 Mar
AU$328
1 Mar - 2 Mar
includes taxes & fees
Paradise Point Resort & Spa: Family-friendly resort with free WiFi and 5 outdoor pools. Located on the waterfront.
Spacious, nice rooms, beautiful resort, lots of activities. Only downside is $50 per night for parking by the room, though there is public parking on the property that we were not aware of.

Reviewed on 8 Feb 2026

Opens in a new windowParadise Point Resort & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.