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Residence Inn By Marriott Jacksonville - Mayo Clinic Area

3.0 star property

Photo gallery for Residence Inn By Marriott Jacksonville - Mayo Clinic Area

A spacious living area with a high ceiling, a fireplace, and a bar area in the background.
A reception area with a brick wall, large windows with sheer curtains, and a modern desk setup.
A multi-story hotel with a central entrance, surrounded by well-maintained lawns and palm trees.
A modern kitchen with a bar area, seating, and a view of the outdoors.
An outdoor patio area with seating and a central fire feature, surrounded by buildings and palm trees.

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Pet-friendly
  • Parking included
  • Free Wi-Fi
  • Air-conditioning
The current price is AU$240
includes taxes & fees
8 Aug - 9 Aug

Explore the area

View map
4905 SAN PABLO ROAD SOUTH, Jacksonville, FL, 32224
  • Place, University of North Florida
    ‪5 min drive‬
  • Place, St. Johns Town Center
    ‪8 min drive‬
  • Place, Mayport Naval Station
    ‪21 min drive‬
  • Airport, Jacksonville, FL (JAX-Jacksonville Intl.)
    ‪34 min drive‬

Room options

View all photos for Studio, 1 King Bed with Sofa bed, Corner

A modern hotel room with a bed, desk, chair, TV, and large windows with curtains.

Studio, 1 King Bed with Sofa bed, Corner

9.8 out of 10
Exceptional
(6 reviews)
  • 50 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio Suite, 1 Bedroom, Corner

A modern kitchen with wooden cabinets, a dishwasher, and a countertop with kitchenware. There is a dining area with a table and chairs, and a living room with a sofa and a TV on the wall.

Studio Suite, 1 Bedroom, Corner

10.0 out of 10
Exceptional
(4 reviews)
  • 60 sq m
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio Suite, 1 King Bed with Sofa bed

A modern kitchen with wooden cabinets, a built-in microwave, and a dishwasher.

Studio Suite, 1 King Bed with Sofa bed

9.6 out of 10
Exceptional
(100 reviews)
  • 38 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio Suite, 1 Bedroom

A modern hotel room with a grey sofa, a small round table, a desk with a chair, and a flat-screen TV mounted on the wall.

Studio Suite, 1 Bedroom

9.8 out of 10
Exceptional
(23 reviews)
  • 52 sq m
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

A hotel room with a large bed, two bedside tables, and a nightstand with a phone.

Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Tub)

9.0 out of 10
Wonderful
(8 reviews)
  • 38 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio Suite, 1 King Bed with Sofa bed (Hearing Accessible)

A hotel room with a large bed, two bedside tables, and a nightstand with a phone.

Studio Suite, 1 King Bed with Sofa bed (Hearing Accessible)

9.0 out of 10
Wonderful
(2 reviews)
  • 38 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Roll-In Shower)

A hotel room with a large bed, two bedside tables, and a nightstand with a phone.

Studio Suite, 1 King Bed with Sofa bed (Mobility Accessible, Roll-In Shower)

10.0 out of 10
Exceptional
(1 review)
  • 38 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio Suite, 1 Bedroom (Hearing Accessible)

A modern hotel room with a sofa, desk, and kitchenette.

Studio Suite, 1 Bedroom (Hearing Accessible)

8.0 out of 10
Very good
(1 review)
  • 52 sq m
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio, 1 King Bed with Sofa bed, Corner (Hearing Accessible)

A modern hotel room with a bed, desk, chair, TV, and large windows with curtains.

Studio, 1 King Bed with Sofa bed, Corner (Hearing Accessible)

9.0 out of 10
Wonderful
(2 reviews)
  • 50 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Studio Suite, 1 Bedroom, Corner (Mobility/Hearing Access, Roll-In Shwr)

A modern hotel room with a sofa, desk, and kitchenette.

Studio Suite, 1 Bedroom, Corner (Mobility/Hearing Access, Roll-In Shwr)

  • 60 sq m
  • 1 bedroom
  • Sleeps 5
  • 2 Queen Beds and 1 Double Sofa Bed
  • Free Wi-Fi

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About the area

Jacksonville

At Residence Inn By Marriott Jacksonville - Mayo Clinic Area you'll be within a 10-minute walk of Mayo Clinic Florida and 2.7 km (1.7 mi) from Harbor City Municipal Golf Course. Highlights at this hotel include an outdoor swimming pool, a complimentary breakfast and in-room kitchens. .At the hotel's own lounge bar or poolside bar, you can enjoy a drink. Enjoy the 24-hour gym and pool loungers. 2678 square feet (249 square metres) of event facilities include 2 meeting rooms and conference space, and other business amenities include a 24-hour business centre and coworking space. Added amenities include free Wi-Fi in public areas, coffee/tea in a common area and laundry facilities. There's also the convenience of free self parking. .Attractions within a 10-minute drive of this 3-property class Isle of Palms hotel include St. Johns Town Center and University of North Florida.

What's nearby

  • University of North Florida - 5 min drive - 9.0 km
  • St. Johns Town Center - 8 min drive - 12.6 km
  • Jacksonville Beach Pier - 12 min drive - 10.4 km
  • Mayport Naval Station - 21 min drive - 18.6 km
  • EverBank Stadium - 21 min drive - 30.2 km

Getting around

  • Jacksonville, FL (CRG-Jacksonville Executive at Craig) - 17 min drive

Restaurants

  • ‪Culver’s - ‬4 min drive
  • ‪Circle K - ‬9 min walk
  • ‪Starbucks - ‬4 min drive
  • ‪Mayo Clinic - Employee Cafeteria - ‬18 min walk
  • ‪M Brothers at Mayo - ‬17 min walk

About this property

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area offers its guests an outdoor pool and a 24-hour fitness centre. You can enjoy a drink at one of the bars, which include a poolside bar and a bar/lounge. Free breakfast is served daily. A computer station is on site and WiFi is free in public spaces.

A 24-hour business centre, 2 meeting rooms, and coworking spaces are available. Event space at this hotel measures 2678 square feet (249 square metres) and includes conference space. Barbecue grills, multilingual staff, and a garden are also featured at the business-friendly Residence Inn By Marriott Jacksonville - Mayo Clinic Area. Self parking is free.

This 3-star Jacksonville hotel is smoke free.

  • 1 building
  • 155 guestrooms or units
  • 7 levels
  • 2678 sq ft of conference space
  • 249 sq. m of conference space
  • Built in 2020
  • Buffet breakfast (free)
  • Poolside lounge chairs
  • Business centre (24 hours)
  • Conference space
  • Coffee in lobby
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-out
  • Staff members are multilingual
  • Storage area for luggage
  • Front desk safe
  • Concierge
  • Food/drink service (free)
  • Wedding services available
  • Corner/local shop
  • Garden
  • BBQ grill(s)
  • Outdoor picnic space
  • Newspapers in lobby (free)
  • Fireplace in lobby
  • Television in lobby
  • Lift
  • No smoking on site
  • Water dispenser
  • Bar or lounge
  • Bar by the pool
Residence Inn By Marriott Jacksonville - Mayo Clinic Area offers 155 air-conditioned accommodations with laptop-compatible safes and coffee/tea makers. This accommodation offers separate sitting areas. 55-inch Smart televisions come with premium cable channels and Netflix. Accommodation at this 3-star hotel has kitchens with fridges, stovetops, microwaves and separate dining areas. Bathrooms include baths or showers, complimentary toiletries and hairdryers.

This Jacksonville hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and telephones. Additionally, rooms include an iron/ironing board and blackout curtains. Housekeeping is offered on a daily basis and change of bedsheets can be requested. Housekeeping is provided on request.

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Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
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  • Pool
  • Breakfast included
  • Pet-friendly
  • Parking included
4.5 out of 5, Wonderful, 1,001 reviews
The price is AU$209
includes taxes & fees
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Free uncovered self parking on site
  • Limited on-site self parking
  • Wheelchair-accessible parking and van parking available

Food and drink

  • Free buffet breakfast available 6:30 AM to 9:00 AM on weekdays and 7:00 AM to 9:30 AM on weekends
  • A bar/lounge
  • A poolside bar
  • Coffee and tea in common areas

Things to do

  • 24-hour gym
  • Outdoor pool
  • TV in common areas

Family friendly

  • Grocery/convenience store
  • In-room kitchen
  • In-room microwave
  • In-room refrigerator
  • Laundry facilities
  • Outdoor pool
  • Separate in-room dining area

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Water dispenser

Guest services

  • Change of bedsheets (on request)
  • Concierge services
  • Dry cleaning/laundry service
  • Free grocery shopping service
  • Housekeeping (daily)
  • Multilingual staff
  • Wedding services

Business services

  • 2 meeting rooms
  • 2,678 square feet of conference space
  • 24-hour business centre
  • Computer station
  • Coworking space

Outdoors

  • Barbecue grill
  • Garden
  • Picnic area
  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Accessible bathtub
  • Assistive listening devices
  • Assistive listening devices in meeting rooms
  • Bathroom emergency pull cord
  • Braille/raised signage
  • Grab bar near toilet
  • Hand-held showerhead
  • Handrails in stairways
  • Height-adjustable showerhead
  • Lever door handles
  • Lift
  • Low-height bed
  • Low-height counter and sink
  • Low-height door lock
  • Low-height electrical sockets in bathroom
  • Low-height view port in door
  • Phone accessibility kit
  • Pool hoist on site
  • Raised toilet seat
  • Stair-free path to entrance
  • Vibrating pillow alarm
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible business centre
  • Wheelchair-accessible concierge desk
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible van parking
  • Wheelchair-width doorways

More

  • 1 building
  • 7 floors
  • Ballroom
  • Banquet hall
  • Built in 2020
  • Communal living room
  • Comprehensive food waste policy
  • Double-glazed windows
  • Fireplace in lobby
  • No plastic coffee stirrers
  • Non-plastic coffee stirrers available
  • Smoking not allowed
  • Some LED lighting used
  • Traditional architecture
  • Vegan dining options
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Bathtub or shower
  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 55-inch smart TV with premium cable channels
  • Netflix
  • Streaming services

Food and drink

  • Coffee/tea maker
  • Cookware, dishware, and utensils
  • Dishwasher
  • Hob
  • Kitchen
  • Microwave
  • Refrigerator
  • Separate dining area
  • Toaster

More

  • Air conditioning
  • Connecting rooms available
  • Desk
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Phone
  • Recycling
  • Separate sitting area
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 6:00 AM
Contactless check-in and check-out are available
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM
Contactless check-out
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 150 per accommodation, per stay
  • Only dogs and cats are allowed
  • Maximum 2 (weight limit: 40 lb per pet)
  • Restrictions apply
  • For more information, you can reach out to the property at the number on the booking confirmation
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Cots (infant beds) are not available.

Payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Deposit: USD 125 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Pet fee: USD 150 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector and window guards
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, Mastercard, American Express, Discover and Diners Club. Cash is not accepted. For guests' safety, the property includes a carbon monoxide detector, a fire extinguisher, a smoke detector and window guards in all accommodation. Cashless payment methods are available for all transactions and guests can access their rooms with a mobile device. This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Marriott) guidelines.

We should mention

  • Registered guests are the only ones allowed to be in guestrooms.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • To make arrangements to bring your pet, contact the property directly at the number on your booking confirmation (please see the Fees section for related charges).
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Residence INN BY Marriott Jacksonville
Residence Inn by Marriott Jacksonville East
Residence Inn Jacksonville Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic Area Hotel

Frequently asked questions

What is the cancellation policy at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

Residence Inn By Marriott Jacksonville - Mayo Clinic Area offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

As of 30 July 2026, prices found for a 1-night stay for 2 adults at Residence Inn By Marriott Jacksonville - Mayo Clinic Area on 8 Aug 2026 start from AU$240, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

Yep, Residence Inn By Marriott Jacksonville - Mayo Clinic Area has a free self car park.

Are there any beaches close to Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

The closest beach to Residence Inn By Marriott Jacksonville - Mayo Clinic Area is Northeast Florida Beaches (5.9 km).

Does Residence Inn By Marriott Jacksonville - Mayo Clinic Area have a pool?

Residence Inn By Marriott Jacksonville - Mayo Clinic Area has an outdoor pool. Grab your bathers and lounge poolside while enjoying on a lounger and with a coldie from the bar.

Does Residence Inn By Marriott Jacksonville - Mayo Clinic Area serve breakfast?

Yeah, free buffet brekkie is served on weekdays from 6:30 AM to 9:00 AM and weekends from 7:00 AM to 9:30 AM.

Is there a free airport shuttle available at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

No, Residence Inn By Marriott Jacksonville - Mayo Clinic Area does not offer an airport shuttle service.

What time are check-in & check-out at Residence Inn By Marriott Jacksonville - Mayo Clinic Area?

Check-in begins at 4:00 PM. Check-out time is 11:00 AM.

Residence Inn By Marriott Jacksonville - Mayo Clinic Area Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 455 out of 566 reviews
Rating 8 - Good. 75 out of 566 reviews
Rating 6 - Okay. 14 out of 566 reviews
Rating 4 - Poor. 14 out of 566 reviews
Rating 2 - Terrible. 8 out of 566 reviews

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

Reviews

Verified

8/10 Good

Nancy

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean room, staff were very helpful, room was comfortable
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Sabrena

Great stay! Clean room, friendly staff.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

STEVEN

Liked: Cleanliness, staff & service, amenities
Conveniently located, clean rooms, excellent breakfast
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

Vashti

Liked: Cleanliness, staff & service, property conditions & facilities
Good breakfast
Stayed 4 nights in Apr 2026
Verified

10/10 Excellent

Jill

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Location was very perfect for an appointment at The Mayo Clinic. Staff could not have been nicer.
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Darlene

Liked: Cleanliness, amenities, property conditions & facilities
Clean room, amazing staff great location
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The motel was clean inside and out food was excellent staff was nice and friendly shuttle to and from the mayo clinic was a blessing not to have to worry about driving in traffic they also would shop for groceries for you all you had to do was give them a list I recommend staying there loved it
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Anthony

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean and well equipped room. Very good buffet breakfast
Stayed 3 nights in Apr 2026
Verified

8/10 Good

M

Liked: Cleanliness, staff & service, property conditions & facilities
Good location to multiple attractions in the city. Love the free and easily accessible parking.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

JOHN

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast was ok nothing special but the staff were all helpful and upbeat. Would highly recommend this property especially if you’re going to Mayo Clinic.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

clipper

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Large well laid out rooms!
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Teresa

Liked: Amenities, property conditions & facilities
Everything was wonderful. I recommend this property.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

John

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Everything was nice and was able to use all things. The pool was even heated. Very nice.
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Astraes

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the size of the rooms, the kitchen, the amazing breakfast and the helpful staff. Only complaint would be to have more towels available.
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Zonia

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
perfect
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Vivien

Liked: Cleanliness, amenities, property conditions & facilities
Gret Hotel
Stayed 6 nights in Feb 2026
Verified

10/10 Excellent

Raymond

Liked: Cleanliness, staff & service, amenities
Wonderful room, clean and comfortable. The staff is great
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

james

Liked: Cleanliness, staff & service, property conditions & facilities
Excellent place to Stay!!
Stayed 1 night in Jul 2025
Verified

10/10 Excellent

Tiana

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Based on my status was able to get a late checkout with no issue.
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Gary

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great facility to stay.
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Stephen

Liked: Cleanliness, amenities, property conditions & facilities
Great room
Stayed 1 night in Feb 2026
Verified

8/10 Good

Kimberly

Liked: Cleanliness, staff & service, amenities
Clean rooms and amenities.
Stayed 4 nights in Jan 2026
Verified

10/10 Excellent

Priscilla

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Quality throughout the hotel. Open front lounge area with comfortable seating and lighting. Parking lot has great lighting and access to facility. Transportation available to and from Mayo Clinic.
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Kay

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Always comfortable, beautiful rooms, great beds, great service, spotless clean
Stayed 1 night in Oct 2025
Verified

10/10 Excellent

Bonnie

Liked: Cleanliness, staff & service, property conditions & facilities
Very nice hotel - clean, quiet and the most convenient to the Mayo Clinic.
Stayed 1 night in Nov 2025

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