Flights from Orlando (MCO) to Knoxville (TYS)

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Orlando to Knoxville Flight Information

Find the Cheapest Flights from Orlando (MCO) to Knoxville (TYS)

Work hard, travel harder! Wotif brings you the cheapest Orlando to Knoxville flights, making it possible to have a five star holiday without that five star price tag. Browse and compare our top MCO to TYS routes and airport options. So, go ahead and treat yourself, your sweetheart, or the kids to an unforgettable holiday this year.

to Information

Traveling From
Orlando Intl.
Origin Airport
Origin Airport IATA Code
MCO
Traveling To
McGhee Tyson
Destination Airport
Destination Airport IATA Code
TYS
Number of Airlines Serving
Average Flight Time
hours mins
Direct Flight Time
hours mins
Flight Price
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time zone:
America/New_York
Address:
One Airport Boulevard
Orlando FL, 32827-4399
United States
IATA code:
MCO
Longitude:
-81.308301
Latitude:
28.432177
Time zone:
America/New_York

Orlando to Knoxville Flight Deals from

Considering a quick trip to Knoxville, but not sure which is the best route for you? Well, you’re in luck! Wotif has done the hard work, so all you need to do is check out these flights from MCO to TYS. With heaps of cheap fares from Orlando, we guarantee you’ll be arriving to your holiday destination in style without emptying your bank account in the process.

It’s easy to book flights to Knoxville from Orlando  

For a huge choice of flights, simply enter your travel dates and hit search and we’ll hunt out fantastic deals on one-way, return and multi-city airfares to Knoxville from Orlando from different airlines. If you click the ‘direct flights’ box, you see flights that’ll get you to Knoxville in just hour(s) and mins, too.   

Snap up great deals on flights to Knoxville from Orlando 

Choose from flights a day on average, with prices starting at and rising to depending on the cabin class, travel dates, and airline carrier. And if you’re up for a last-minute getaway, you can get great deals on flights from Orlando to Knoxville today!  

Find cheap airfares to Knoxville from Orlando 

Here are our insider tips for bagging a flight bargain: 

  • Look for midweek flights and late night, early morning arrival and departure times
  • Check out other airports near Orlando and Knoxville
  • Avoid peak season (prices tend to be lower in )
  • Be flexible with your travel dates and you can usually get cheaper options  

Reasons to book your flights to Knoxville from Orlando with Wotif

Wotif is a super-easy way to find the best flight for you to Knoxville. Get more bang for your buck on flight and hotel or car rental combos and download the free Wotif app to tap into exclusive deals. Book now with Wotif and have a great flight!

 

Great places to stay after flight from Orlando to Knoxville

Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy, Alcoa, TN
The price is AU$214 per night from 16 Nov to 17 Nov
AU$214
16 Nov - 17 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff and the clean ...
9/10 Wonderful! (1,028 reviews)
We stayed here on a last minute canceled flight and we enjoyed ourselves. The hotel staff and shuttle were great! Thank you!

Reviewed on 25 Oct 2025

Hilton Knoxville Airport
La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road, Alcoa, TN
The price is AU$132 per night from 16 Nov to 17 Nov
AU$132
16 Nov - 17 Nov
includes taxes & fees
Stay at this 3-star business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
8.8/10 Excellent! (1,632 reviews)
It was a convenient place to stay. Quiet, comfortable and in need of some updating.

Reviewed on 27 Oct 2025

La Quinta Inn & Suites by Wyndham Knoxville Airport
Best Western Knoxville Airport/Alcoa

Best Western Knoxville Airport/Alcoa

2.5 out of 5
162 Cusick Rd, Alcoa, TN
The price is AU$129 per night from 9 Nov to 10 Nov
AU$129
9 Nov - 10 Nov
includes taxes & fees
Book a stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean rooms ...
8.4/10 Very Good! (1,027 reviews)
When we checked out 10-25 at 6:30 AM there was no breakfast available.

Reviewed on 25 Oct 2025

Best Western Knoxville Airport/Alcoa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More Destinations

^Savings based on all package bookings made with Flight + Hotel on Wotif.com from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.