Flights from Orlando (MCO) to Knoxville (TYS)

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Orlando to Knoxville Flight Information

Find the Cheapest Flights from Orlando (MCO) to Knoxville (TYS)

Work hard, travel harder! Wotif brings you the cheapest Orlando to Knoxville flights, making it possible to have a five star holiday without that five star price tag. Browse and compare our top MCO to TYS routes and airport options. So, go ahead and treat yourself, your sweetheart, or the kids to an unforgettable holiday this year.

to Information

Traveling From
Orlando Intl.
Origin Airport
Origin Airport IATA Code
MCO
Traveling To
McGhee Tyson
Destination Airport
Destination Airport IATA Code
TYS
Number of Airlines Serving
Average Flight Time
hours mins
Direct Flight Time
hours mins
Flight Price
Address:
2055 Alcoa Highway
Knoxville TN, 37701
United States
IATA code:
TYS
Longitude:
-83.989729
Latitude:
35.80565
Time zone:
America/New_York
Address:
One Airport Boulevard
Orlando FL, 32827-4399
United States
IATA code:
MCO
Longitude:
-81.308301
Latitude:
28.432177
Time zone:
America/New_York

Orlando to Knoxville Flight Deals from

Considering a quick trip to Knoxville, but not sure which is the best route for you? Well, you’re in luck! Wotif has done the hard work, so all you need to do is check out these flights from MCO to TYS. With heaps of cheap fares from Orlando, we guarantee you’ll be arriving to your holiday destination in style without emptying your bank account in the process.

It’s easy to book flights to Knoxville from Orlando  

For a huge choice of flights, simply enter your travel dates and hit search and we’ll hunt out fantastic deals on one-way, return and multi-city airfares to Knoxville from Orlando from different airlines. If you click the ‘direct flights’ box, you see flights that’ll get you to Knoxville in just hour(s) and mins, too.   

Snap up great deals on flights to Knoxville from Orlando 

Choose from flights a day on average, with prices starting at and rising to depending on the cabin class, travel dates, and airline carrier. And if you’re up for a last-minute getaway, you can get great deals on flights from Orlando to Knoxville today!  

Find cheap airfares to Knoxville from Orlando 

Here are our insider tips for bagging a flight bargain: 

  • Look for midweek flights and late night, early morning arrival and departure times
  • Check out other airports near Orlando and Knoxville
  • Avoid peak season (prices tend to be lower in )
  • Be flexible with your travel dates and you can usually get cheaper options  

Reasons to book your flights to Knoxville from Orlando with Wotif

Wotif is a super-easy way to find the best flight for you to Knoxville. Get more bang for your buck on flight and hotel or car rental combos and download the free Wotif app to tap into exclusive deals. Book now with Wotif and have a great flight!

 

Great places to stay after flight from Orlando to Knoxville

La Quinta Inn & Suites by Wyndham Knoxville Airport

La Quinta Inn & Suites by Wyndham Knoxville Airport

3 out of 5
126 Cusick Road Alcoa TN
The price is AU$127 per night from 22 Mar to 23 Mar
AU$127
22 Mar - 23 Mar
includes taxes & fees
Stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their ...
8.8/10 Excellent! (1,786 reviews)
Driving in and out of the hotel lot was very dangerous. It was very difficult to make a left turn across the lanes of highway traffic. The condition of the hotel was okay. The trash bins were always full and needed attention. The staff was very nice and friendly.

Reviewed on 13 Mar 2026

La Quinta Inn & Suites by Wyndham Knoxville Airport
Hilton Knoxville Airport

Hilton Knoxville Airport

3.5 out of 5
2001 Alcoa Hwy Alcoa TN
The price is AU$214 per night from 5 Apr to 6 Apr
AU$214
5 Apr - 6 Apr
includes taxes & fees
Stay at this family-friendly hotel in Alcoa. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the helpful staff and the clean rooms ...
9.2/10 Wonderful! (1,001 reviews)
It was OK. It was comfortable. We had everything we needed. The bar was good, had food. Easy in, easy out. What more is there to say?

Reviewed on 13 Mar 2026

Hilton Knoxville Airport
Tru by Hilton Alcoa Knoxville Airport

Tru by Hilton Alcoa Knoxville Airport

2.5 out of 5
125 FURROW WAY Alcoa TN
The price is AU$139 per night from 22 Mar to 23 Mar
AU$139
22 Mar - 23 Mar
includes taxes & fees
Stay at this business-friendly hotel in Alcoa. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (687 reviews)
Great stay!

Reviewed on 12 Mar 2026

Tru by Hilton Alcoa Knoxville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More Destinations

^Savings based on all package bookings made with Flight + Hotel on Wotif.com from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.