
American Airlines Flights from Chicago (ORD) to Southampton (SOU)
Change your flight without a fee on select flights
Money Saving Bundle when you purchase Hotel + Flight!
Get mobile alerts about flight delays, gate changes and more with the FREE Wotif app
American Airlines Flights from ORD to SOU
How much is a American Airlines flight from Chicago (ORD) to Southampton (SOU)?
One-way flights start as little as and there are roundtrips available from . Get in! You can score some sweet deals with Wotif and American Airlines.
How many non-stop American Airlines flights from Chicago (ORD) to Southampton (SOU) are there per day?
American Airlines flies flights direct every day between Chicago (ORD) and Southampton (SOU).
How far is Chicago (ORD) from Southampton (SOU)?
It’s from Chicago (ORD) to Southampton (SOU).
What is the best airline to fly from O'Hare Intl.?
At Wotif, we give you all the available options from our reputable partners. Select the airline that best suits your preferences and membership loyalties. You can fly from O'Hare Intl. with: .
Can I change or cancel my American Airlines tickets from Chicago to Southampton on Wotif?
Change of plans? No worries! We’re right here to make things as easy as possible. Check out the American Airlines rules and restrictions in your itinerary. You can also use the No Change Fees filter to find flexible plane tickets for future trips. For more information on how to cancel or change your flight on Wotif, visit our customer service portal.
How do I find the best deal on American Airlines flights from Chicago (ORD) to Southampton (SOU)?
Just review and compare all our awesome offers or enter your travel dates to see more terrific deals on American Airlines flights from Chicago. And remember you can save even more when you bundle a hotel with your flight as part of a Wotif package. Sweet!
What’s a good way to get cheap American Airlines flight tickets from Chicago to Southampton?
We have loads of cheap flights, so just enter your travel dates to see what’s available. If you can be flexible on when you fly, you’ll find even more epic flight deals. So get booking!
What is the cheapest time of year to fly from Chicago (ORD) to Southampton (SOU)?
The cheapest time of the year for a return trip is . One-way, the cheapest month to fly is . Check our deal cards for details.
How long does it take to fly from ORD to SOU?
It typically takes hours to fly directly from Chicago (ORD) to Southampton (SOU).
Epic Hotel in Southampton

Village Hotel Southampton Eastleigh
Reviewed on 22 Jun. 2025

Holiday Inn Express Southampton M27 Jct7 by IHG
Reviewed on 20 Jul. 2025

DoubleTree by Hilton Southampton
Reviewed on 18 Jul. 2025
Discover top hotels, vacation package, cheap car rental deals and more with Wotif!
Domestic to International Routes
- Sydney to Honolulu (SYD - HNL)
- Sydney to San Francisco (SYD - SFO)
- Sydney to Amsterdam (SYD - AMS)
- Sydney to London (SYD - LHR)
- Melbourne to Chicago (MEL - ORD)
- Brisbane to London (BNE - LHR)
- Sydney to Vancouver (SYD - YVR)
- Brisbane to London (BNE - LHR)
- Brisbane to Chicago (BNE - ORD)
- Melbourne to Vancouver (MEL - YVR)
Domestic Routes
- Sydney to Vancouver (SYD - YVR)
- Brisbane to Amsterdam (BNE - AMS)
- Sydney to Los Angeles (SYD - LAX)
- Chicago to Amsterdam (ORD - AMS)
- Melbourne to Vancouver (MEL - YVR)
- Sydney to Amsterdam (SYD - AMS)
- Brisbane to London (BNE - LHR)
- Adelaide to Salt Lake City (ADL - SLC)
- Sydney to San Francisco (SYD - SFO)
- Melbourne to Honolulu (MEL - HNL)
Destinations For You
- British Airways Sydney (SYD) to London (LHR) flights
- Airfares from Brisbane (BNE) to Manchester (MAN)
- Airfares from Melbourne (MEL) to London (LHR)
- Qantas Airways Melbourne (MEL) to London (LHR) flights
- Qantas Airways Brisbane (BNE) to London (LHR) flights
- Royal Brunei Airlines Melbourne (MEL) to London (LHR) flights
- Airfares from London (LHR) to Perth (PER)
- Singapore Airlines Sydney (SYD) to London (LHR) flights
- Qatar Airways Sydney (SYD) to London (LHR) flights
- Emirates Sydney (SYD) to London (LHR) flights
- Qantas Airways Perth (PER) to London (LHR) flights
- Airfares from London (LHR) to Melbourne (MEL)
- Emirates Brisbane (BNE) to London (LHR) flights
- Airfares from Sydney (SYD) to Manchester (MAN)
- Airfares from Brisbane (BNE) to London (LHR)
- British Airways London (LHR) to Sydney (SYD) flights
- Airfares from Perth (PER) to London (LHR)
- Emirates Adelaide (ADL) to Gatwick (LGW) flights
- Airfares from Sydney (SYD) to London (LHR)
- Emirates Melbourne (MEL) to London (LHR) flights
- Airfares from London (LHR) to Brisbane (BNE)
- Singapore Airlines Melbourne (MEL) to London (LHR) flights
- Virgin Atlantic Sydney (SYD) to London (LHR) flights
- Qatar Airways Perth (PER) to London (LHR) flights
- Qantas Airways Sydney (SYD) to London (LHR) flights
- Singapore Airlines Brisbane (BNE) to London (LHR) flights
- British Airways London (LHR) to Perth (PER) flights
- Airfares from Adelaide (ADL) to London (LHR)
- Qatar Airways Adelaide (ADL) to London (LHR) flights
- Qantas Airways London (LHR) to Sydney (SYD) flights
^Savings based on all package bookings made with Flight + Hotel on Wotif.com from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.