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21C Museum Hotel St Louis

4.5 star property
Luxury hotel with fitness centre and steam room

Photo gallery for 21C Museum Hotel St Louis

Exterior
Massages
Bar (on property)
Dining
Indoor pool

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Bar
The current price is AU$302
includes taxes & fees
22 May - 23 May

Explore the area

Map
1528 Locust street, St. Louis, MO, 63103
  • Enterprise Center
    ‪8 min walk‬
  • St. Louis Union Station
    ‪12 min walk‬
  • Busch Stadium
    ‪18 min walk‬
  • St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪26 min drive‬

Room options

Loft, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Bathrobes
Hairdryer
Private bathroom
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room (Bunk Bed)

Room (Bunk Bed)

Room (Bunk Bed)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Separate bedroom
Bathrobes
Hairdryer
  • Sleeps 2
  • 1 Single Bunk Bed

Deluxe Room, Accessible (Accessible)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Bathrobes
Hairdryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Hairdryer
Bathrobes
Free bottled water
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Hairdryer
Bathrobes
Free bottled water
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Bathrobes
Hairdryer
Private bathroom
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Hairdryer
Bathrobes
Free bottled water
  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Double Room, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Bathrobes
Private bathroom
Shower/bath combination
  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Hairdryer
Bathrobes
Free bottled water
  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

Room, 1 King Bed, Corner

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Bathrobes
Hairdryer
Private bathroom
  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

In-room safe, desk, laptop workspace, blackout curtains

Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Bathrobes
Hairdryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Bathrobes
Hairdryer
Private bathroom
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

In-room safe, desk, laptop workspace, blackout curtains

Luxury Double Room, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Blackout curtains
Bathrobes
Private bathroom
Shower/bath combination
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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About the area

St. Louis

A luxury stay in the heart of St. Louis awaits you at 21C Museum Hotel St Louis . Within just a 10-minute stroll, you'll find popular attractions like Enterprise Center and City Museum. Highlights at this hotel include a restaurant, an indoor swimming pool and a bar/lounge. .Enjoy the gym and steam room. Meeting rooms and a business centre are among the business amenities offered. Other amenities include free Wi-Fi in public areas, a coffee shop/cafe and spa services. Cooked-to-order breakfast is available daily between 6:30 AM and 1:00 PM. There's also the convenience of valet parking. .Within a 15-minute walk of this 4.5-property class Downtown West hotel, attractions include St. Louis Union Station and America's Center Convention Complex.

What's nearby

  • City Museum - 6 min walk - 0.6 km
  • Enterprise Center - 8 min walk - 0.7 km
  • St. Louis Union Station - 12 min walk - 1.0 km
  • Busch Stadium - 18 min walk - 1.6 km
  • Gateway Arch - 4 min drive - 2.7 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • Lambert-St. Louis International Airport (STL) - 26 min drive

Restaurants

  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪Grand Hall Lounge Union Station - ‬11 min walk
  • ‪Hair of the Dog - ‬7 min walk
  • ‪Peabody Lounge - ‬6 min walk
  • ‪Medina Mediterranean Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel with fitness centre and steam room
21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness centre. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business centre and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

  • 104 guestrooms or units
  • Conference rooms
  • Business facilities
  • Breakfast available (surcharge)
  • Dry cleaning
  • Front desk (24 hours)
  • Storage area for luggage
  • Concierge
  • Pool or billiards table
  • ATM
  • Lift
  • No smoking on site
  • Bar or lounge
  • Coffee shop
  • Dining venue
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and a safe. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries and hairdryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs and telephones. Additionally, rooms include complimentary bottles of water and an iron/ironing board. Change of towels and change of bedsheets can be requested. Housekeeping is provided on a daily basis.

Guests can pamper themselves by indulging in the on-site spa services. Services include massages.

Languages

English

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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, Mastercard and American Express. Cash is not accepted. For guests' safety, the property includes a smoke detector and outdoor lighting in all accommodation.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

What is the cancellation policy at 21C Museum Hotel St Louis ?

21C Museum Hotel St Louis offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of 27 Apr 2025, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on 22 May 2025 start from AU$294.55, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at 21C Museum Hotel St Louis ?

Yep, 21C Museum Hotel St Louis has valet parking with in/out privileges for USD 50 per day.

Is there a spa on site at 21C Museum Hotel St Louis ?

There's no onsite spa, but this property does offer services like massages.

Does 21C Museum Hotel St Louis have a pool?

Yep, and guests love it! 21C Museum Hotel St Louis has an indoor pool.

Does 21C Museum Hotel St Louis serve breakfast?

Yeah, cooked-to-order breakfast is offered daily from 6:30 AM to 1:00 PM.

Is there a free airport shuttle available at 21C Museum Hotel St Louis ?

No, 21C Museum Hotel St Louis does not offer an airport shuttle service.

Is there a bar or restaurant at 21C Museum Hotel St Louis ?

Yep, they've got a lounge bar and an onsite restaurant.

What time are check-in & check-out at 21C Museum Hotel St Louis ?

Check-in begins at 4:00 PM. Check-out time is 11:00 AM.

Is there a golf course on site at 21C Museum Hotel St Louis ?

There isn't one on site, but St. Louis Union Station Mini Golf is a short 13-minute walk away.

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 792 out of 1094 reviews
Rating 8 - Good. 169 out of 1094 reviews
Rating 6 - Okay. 61 out of 1094 reviews
Rating 4 - Poor. 32 out of 1094 reviews
Rating 2 - Terrible. 40 out of 1094 reviews

9.4/10

Cleanliness

9.2/10

Staff & service

9.2/10

Amenities

9.4/10

Property conditions & facilities

9.2/10

Eco-friendliness

Reviews

10/10 Excellent

Raven

Liked: Cleanliness, staff & service, property conditions & facilities
It was such cool place! The pool and spa were so fun and Good Press was great for breakfast.
Stayed 2 nights in Jan 2025

10/10 Excellent

Todd, Lake St Louis

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 1 night in Jan 2025

8/10 Good

Monir

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Love the look and people!!
Stayed 2 nights in Dec 2024

10/10 Excellent

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

4/10 Poor

Audrey

Travelled with group
Disliked: Cleanliness, property conditions & facilities
First checked in for my birthday weekend and they didn’t have my room ready until 8:30 PM when check in was at 4. They put us in a temporary room which was a room for one person when we had 4 and which had not been cleaned and other items of other peoples stuff were in there. Only stayed for one night and it ruined the whole reason of a doing a girls night in stl. The front desk was very honest so I appreciated that but she thought I was someone that she checked in and had an attitude at the beginning and I had to let her know that she needed to look up my account before assuming who I was. This was for my birthday and I thought this was going to be the best night but the staff and hotel just made it such a horrible experience for me. I actually started crying with the way they did everything. Just super disappointed because with the right staff and training this hotel could easily be 5 star hotel. I do want to put in here though that the valet parking crew was incredibly nice though and seem to really care.
Stayed 1 night in Jan 2025

10/10 Excellent

Renee

Liked: Cleanliness, staff & service, property conditions & facilities
We stayed here after the Kody Johnson concert. Quick, convenient walk.
Stayed 1 night in Jan 2025

8/10 Good

Kenneth, Normal

Stayed 1 night in Jan 2025

10/10 Excellent

Bryan Rachel Caughran

Travelled with partner
Liked: Cleanliness, staff & service, property conditions & facilities
Outstanding place, just need a vending machine for snacks.
Stayed 1 night in Jan 2025

10/10 Excellent

Bailey

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Convenient & Clean

Beautiful hotel with a perfect location! Staff was very friendly and vallet was so fast!
Stayed 1 night in Jan 2025

10/10 Excellent

Tylyn

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Super nive4 place little pricy for food but the food is worth it and love the museum and the drinks again a little pricy but is a great time and the staff are so friendly.
Stayed 1 night in Nov 2024

10/10 Excellent

CRISTINA

Travelled with group
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Jan 2025

8/10 Good

David

Liked: Cleanliness
Stayed 5 nights in Jan 2025

10/10 Excellent

Leslie

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

Amy

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

perfect for couples

We stayed at 21C for an overnight getaway. The check in was seamless- the staff was very friendly. Our room was beautiful and clean (was missing body wash but it was quickly rectified). The robes were luxurious, a really nice touch. We enjoyed all of the amenities at the hotel; the pool, hot tub and sauna (all clean and enjoyable), the "nightcap at the museum" and the art museum as well. We had a reservation at the restaurant (best burger in town!) and went back to the bar for dessert and drinks later in the evening (I wish dessert was better). In the morning we went to the coffee shop for breakfast (so delicious!). Everything we needed was right there. The only negatives were; the pillows were not comfortable, the cups in the room for coffee were disposable and not mugs (I prefer mugs and that's what's shown on the website) and I wish parking wasn't so expensive. Overall, a really wonderful experience- we will definitely stay at the 21C again.
Stayed 1 night in Jan 2025

10/10 Excellent

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Stay here instead of a conference hotel!

Lovely two-night stay at the 21c STL. Very reasonable room price, nice bar and very good restaurant, comfy "gameroom" for hanging out. Thoughtful art and interior design as you would expect from a 21c property. Yummy coffee/tea/breakfast shop.
Stayed 2 nights in Jan 2025

8/10 Good

Josh

Stayed 1 night in Jan 2025

8/10 Good

Ana Cecilia Correia

Business traveller
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
More museum than hotel, food options limited and very busy main floor and restaurant
Stayed 6 nights in Dec 2024

10/10 Excellent

Michael

Travelled with family and small children
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Cool spot
Stayed 2 nights in Jan 2025

10/10 Excellent

Kevin, Leawood

Travelled with pets, Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
A Perfectly Curated Wes Anderson-Style Stay at 21c Museum Hotel St. Louis The 21c Museum Hotel in St. Louis is nothing short of extraordinary—a perfectly curated Wes Anderson-esque experience that feels as if you’ve stepped into a cinematic dream. From the moment we arrived, we were immersed in the hotel’s vibrant yet sophisticated aesthetic, seamlessly blending artistry and luxury. Our corner suite was a highlight, featuring impeccable design and one of the most stunning bathrooms we’ve ever seen. Every detail, from the decor to the amenities, exuded thoughtful elegance. The spacious layout and expansive views made it a true haven of relaxation. The hotel’s dedication to merging art and hospitality sets it apart. Wandering through the gallery-like spaces was a delightful experience, with each piece adding to the hotel’s unique charm. The staff was attentive and welcoming, ensuring our stay was flawless from start to finish. This was, without a doubt, one of the finest hotels we’ve ever stayed at. We are eagerly anticipating our return, this time to indulge in the duplex 21c Suite, which promises an even more extraordinary stay. For anyone seeking an unforgettable blend of art, design, and luxury, the 21c Museum Hotel St. Louis is an absolute must-visit.

10/10 Excellent

KELLIE

Stayed 1 night in Dec 2024

10/10 Excellent

Staci

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 2 nights in Dec 2024

8/10 Good

Verified traveller

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jan 2025

10/10 Excellent

John

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
How friendly the velet parking people were. Didnt really car for it being a lane pool and how expiedia stated the rooms were sound proof when they were not. But other than that it was an amazing stay!
Stayed 2 nights in Jan 2025

10/10 Excellent

Becky

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Perfection!

10 out of 10. This will be our new STL staycation when we need a night away. Restaurant was fabulous - food drinks and service all outstanding - then strolled thru the museum for some culture with a drink bf calling it a night. Next time would love to enjoy the pool, hot tub and spa!
Stayed 1 night in Jan 2025

10/10 Excellent

Patrice

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great stay in unique hotel

I had a great stay. The property was very unique. I loved the museum and decor. The restaurant and bar had great food. I also enjoyed the fitness and pool areas. If I’m in the city I would stay again.
Pool area
Potatoes
Soup
Churros
Stayed 2 nights in Oct 2024