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21C Museum Hotel St Louis

4.5 star property

Photo gallery for 21C Museum Hotel St Louis

Restaurant
In-room safe, desk, laptop workspace, blackout curtains
Exterior
Indoor pool
Suite, 1 King Bed (21C)

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Pet-friendly
  • Free Wi-Fi
  • Air-conditioning
The current price is AU$274
includes taxes & fees
21 June - 22 June

Explore the area

View map
1528 Locust street, St. Louis, MO, 63103
  • Place, City Museum
    ‪5 min walk‬
  • Place, St. Louis Union Station
    ‪8 min walk‬
  • Place, Enterprise Center
    ‪8 min walk‬
  • Airport, St. Louis, MO (STL-Lambert-St. Louis Intl.)
    ‪20 min drive‬

Room options

View all photos for Deluxe Room, 1 King Bed

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(112 reviews)
  • 29 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Luxury Double Room, 2 Queen Beds

A hotel room with two beds, a bedside table with a lamp, a vase with flowers, and a book.

Luxury Double Room, 2 Queen Beds

9.4 out of 10
Exceptional
(35 reviews)
  • 39 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for Room (Bunk Bed)

A modern hotel room with a bunk bed, a round table with a plant, an orange armchair, and a colorful abstract painting on the wall.

Room (Bunk Bed)

8.4 out of 10
Very good
(7 reviews)
  • 22 sq m
  • Sleeps 2
  • 1 Single Bunk Bed
  • Free Wi-Fi

View all photos for Loft, 2 Queen Beds

A hotel room with two beds, a large padded headboard, a TV mounted on the wall, and a view of the city through a large window.

Loft, 2 Queen Beds

9.0 out of 10
Wonderful
(2 reviews)
  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for Deluxe Room, Accessible (Accessible)

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Room, Accessible (Accessible)

10.0 out of 10
Exceptional
(1 review)
  • 25 sq m
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Suite, 1 King Bed (21C)

A hotel room with a bed, bedside tables, a lamp, a mirror, and a patterned wall.

Suite, 1 King Bed (21C)

  • 104 sq m
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library)

Suite, 1 King Bed (Library)

  • City view
  • 68 sq m
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed

Luxury Suite, 1 King Bed

9.4 out of 10
Exceptional
(3 reviews)
  • 51 sq m
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Deluxe Room, 1 Double Bed, Accessible

A hotel room with two beds, a sofa, a television, and a painting on the wall.

Deluxe Room, 1 Double Bed, Accessible

  • 36 sq m
  • Sleeps 4
  • 1 Double Bed
  • Free Wi-Fi

View all photos for Deluxe Suite, 1 Double Bed, Accessible

In-room safe, desk, laptop workspace, blackout curtains

Deluxe Suite, 1 Double Bed, Accessible

  • 48 sq m
  • Sleeps 2
  • 1 Double Bed
  • Free Wi-Fi

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About the area

St. Louis

A luxury stay in the heart of St. Louis awaits you at 21C Museum Hotel St Louis . Within just a 10-minute stroll, you'll find popular attractions like St. Louis Union Station and City Museum. Highlights at this hotel include a restaurant, an indoor swimming pool and a bar/lounge. .Enjoy the gym and steam room. Meeting rooms and a business centre are among the business amenities offered. Other amenities include free Wi-Fi in public areas, a coffee shop/cafe and spa services. Cooked-to-order breakfast is available daily between 6:30 AM and 1:00 PM. There's also the convenience of valet parking. .Within a 15-minute walk of this 4.5-property class Downtown West hotel, attractions include Enterprise Center and America's Center Convention Complex.

What's nearby

  • Washington Avenue Historic District - 2 min walk - 0.2 km
  • City Museum - 5 min walk - 0.4 km
  • St. Louis Union Station - 8 min walk - 0.7 km
  • Enterprise Center - 8 min walk - 0.7 km
  • St. Louis Aquarium at Union Station - 11 min walk - 1.0 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • Lambert-St. Louis International Airport (STL) - 24 min drive

Restaurants

  • ‪Imo's Pizza Headquarters & Retail Store - ‬7 min walk
  • ‪Budweiser Kiel Club - ‬6 min walk
  • ‪Rosalita's Cantina - ‬6 min walk
  • ‪City Museum Rooftop Cafe - ‬5 min walk
  • ‪Medina Grill - ‬5 min walk

About this property

21C Museum Hotel St Louis

21C Museum Hotel St Louis offers its guests an indoor pool, a steam room, and a fitness centre. There's a restaurant on site, as well as a coffee shop/cafe. You can enjoy a drink at the bar/lounge. WiFi is free in public spaces.

Business amenities include a business centre and meeting rooms. Spa services, a vending machine, and concierge services are also featured at the luxury 21C Museum Hotel St Louis . For a fee, parking is available.

This 4.5-star St. Louis hotel is smoke free.

  • 104 guestrooms or units
  • Conference rooms
  • Business facilities
  • Breakfast available (surcharge)
  • Dry cleaning
  • Front desk (24 hours)
  • Storage area for luggage
  • Concierge
  • Pool or billiards table
  • ATM
  • Lift
  • No smoking on site
  • Bar or lounge
  • Coffee shop
  • Dining venue
21C Museum Hotel St Louis offers 104 air-conditioned accommodations with espresso makers and a safe. Flat-screen televisions come with premium cable channels. Bathrooms include bathrobes, complimentary toiletries and hairdryers.

This St. Louis hotel provides complimentary wireless Internet access. Business-friendly amenities include desks, desk chairs and telephones. Additionally, rooms include complimentary bottles of water and an iron/ironing board. Change of towels and change of bedsheets can be requested. Housekeeping is provided on a daily basis.

Guests can pamper themselves by indulging in the on-site spa services. Services include massages.

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The price is AU$271
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Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)
  • Limited on-site valet parking

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 100 per accommodation, per stay
  • Only dogs are allowed
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher, a smoke detector and outdoor lighting
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, Mastercard and American Express. Cash is not accepted. For guests' safety, the property includes a fire extinguisher, a smoke detector and outdoor lighting in all accommodation.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

What is the cancellation policy at 21C Museum Hotel St Louis ?

21C Museum Hotel St Louis offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of 10 June 2026, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on 21 June 2026 start from AU$274, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at 21C Museum Hotel St Louis ?

Yep, 21C Museum Hotel St Louis has valet parking with in/out privileges for USD 50 per day.

Is there a spa on site at 21C Museum Hotel St Louis ?

There's no onsite spa, but this property does offer services like massages.

Does 21C Museum Hotel St Louis have a pool?

Yep, and guests love it! 21C Museum Hotel St Louis has an indoor pool.

Does 21C Museum Hotel St Louis serve breakfast?

Yeah, cooked-to-order breakfast is offered daily from 6:30 AM to 1:00 PM.

Is there a free airport shuttle available at 21C Museum Hotel St Louis ?

No, 21C Museum Hotel St Louis does not offer an airport shuttle service.

Is there a bar or restaurant at 21C Museum Hotel St Louis ?

Yep, they've got a lounge bar and an onsite restaurant.

What time are check-in & check-out at 21C Museum Hotel St Louis ?

Check-in begins at 4:00 PM. Check-out time is 11:00 AM.

21C Museum Hotel St Louis Reviews

Reviews

9.0

Wonderful

Rating 10 - Excellent. 1338 out of 1902 reviews
Rating 8 - Good. 291 out of 1902 reviews
Rating 6 - Okay. 139 out of 1902 reviews
Rating 4 - Poor. 62 out of 1902 reviews
Rating 2 - Terrible. 72 out of 1902 reviews

9.2/10

Cleanliness

9.0/10

Staff & service

9.0/10

Amenities

9.2/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

Eric

Liked: Cleanliness, amenities, property conditions & facilities
Great place to stay. I recommend it and will stay again.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Tim

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Stay was great and the hotel was a close walk to Enterprise Center.
Stayed 1 night in Mar 2026
Verified

8/10 Good

Kevin

Liked: Cleanliness, staff & service, property conditions & facilities
Unique hotel, would stay again
Stayed 2 nights in Mar 2026
Verified

8/10 Good

Kristen

Liked: Cleanliness, staff & service, amenities
Friendly staff, beautiful atmosphere, modern finishes.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Barry

Liked: Cleanliness, amenities, property conditions & facilities
Great atmosphere, excellent room accommodations. Staff at the Idlewolf restaurant inside the hotel were great, and the happy hour is excellent for the modest price. Will be staying again soon!
Stayed 3 nights in Feb 2026
Verified

10/10 Excellent

Hanna

Liked: Cleanliness, staff & service, amenities
The one of the best hotels in stl
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Robert

Liked: Cleanliness, amenities, property conditions & facilities
Great service. Would definitely stay again
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Kimbriel

Liked: Cleanliness, amenities, property conditions & facilities
Everything was great i can’t wait to stay again
Stayed 2 nights in Jan 2026
Verified

8/10 Good

Valerie

Liked: Staff & service, amenities
Nice room, the hot tub and steam room were fantastic. The staff were friendly and it was convenient to have coffee right downstairs.
Stayed 4 nights in Feb 2026
Verified

10/10 Excellent

anthony

Liked: Cleanliness, amenities, property conditions & facilities
Clean room and the hotel itself is just gorgeous.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Linda

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful, unique hotel. Loved the esthetics and vibe of the entire building.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

steven h

Liked: Cleanliness, staff & service, property conditions & facilities
Such a cool hotel I love the museum on the second floor so interesting and all the penguins food is great restaurants great everything just what a great stay very unique but very quiet very cozy love everything about it. Can’t wait to stay at the other ones.
Stayed 2 nights in Mar 2026
Verified

10/10 Excellent

Tanya

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
So fun and eclectic! !
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Christopher

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great service and vibe. The art exhibit on the second floor is worth the time and free!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Dimitre

Liked: Cleanliness, amenities, property conditions & facilities
Great hotel! Art, food and drinks were fantastic
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Shane

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great atmosphere and amenities.
Stayed 1 night in Dec 2025
Verified

8/10 Good

Devon

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Enjoyed our stay to bring in the new year.
Stayed 2 nights in Dec 2025
Verified

10/10 Excellent

Stacy

Liked: Cleanliness, amenities, property conditions & facilities
Staff was great!
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Elizabeth

Liked: Cleanliness, staff & service, amenities
Great staff and very clean room.
Stayed 1 night in Jan 2026
Verified

10/10 Excellent

Deontae

Liked: Cleanliness, amenities, property conditions & facilities
6 day stay was wonderful
Stayed 6 nights in Dec 2025
Verified

10/10 Excellent

Elizabeth

Liked: Cleanliness, amenities, property conditions & facilities
Beautiful space. Clean room. Friendly staff.
Stayed 1 night in Feb 2026
Verified

8/10 Good

SHELBY

Staff and amenities were great. Bathroom and Carpet clea miess
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Sarah

Liked: Cleanliness, amenities, property conditions & facilities
Pleasant staff
Stayed 3 nights in Feb 2026
Verified

6/10 Okay

Aurora

Liked: Cleanliness
Disliked: Staff & service, amenities
The valet was so nice. She was the best empire
Stayed 1 night in Mar 2026
Verified

10/10 Excellent

Diana

Liked: Cleanliness, property conditions & facilities
Room was clean stuff was friendly and everyone was super nice
Stayed 2 nights in Feb 2026