Flights from Mexico City (MEX) to Santiago (SCL)

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Mexico City to Santiago Flight Information

Find the Cheapest Flights from Mexico City (MEX) to Santiago (SCL)

Work hard, travel harder! Wotif brings you the cheapest Mexico City to Santiago flights, making it possible to have a five star holiday without that five star price tag. Browse and compare our top MEX to SCL routes and airport options. So, go ahead and treat yourself, your sweetheart, or the kids to an unforgettable holiday this year.

to Information

Traveling From
Mexico City Intl.
Origin Airport
Origin Airport IATA Code
MEX
Traveling To
Arturo Merino Benitez
Destination Airport
Destination Airport IATA Code
SCL
Number of Airlines Serving
Average Flight Time
hours mins
Direct Flight Time
hours mins
Flight Price
Address:
Santiago ,
Chile
IATA code:
SCL
Longitude:
-70.793821
Latitude:
-33.397175
Time zone:
America/Santiago
Address:
Mexico City ,
Mexico
IATA code:
MEX
Longitude:
-99.072778
Latitude:
19.435278
Time zone:
America/Mexico_City

Mexico City to Santiago Flight Deals from

Considering a quick trip to Santiago, but not sure which is the best route for you? Well, you’re in luck! Wotif has done the hard work, so all you need to do is check out these flights from MEX to SCL. With heaps of cheap fares from Mexico City, we guarantee you’ll be arriving to your holiday destination in style without emptying your bank account in the process.

It’s easy to book flights to Santiago from Mexico City  

For a huge choice of flights, simply enter your travel dates and hit search and we’ll hunt out fantastic deals on one-way, return and multi-city airfares to Santiago from Mexico City from different airlines. If you click the ‘direct flights’ box, you see flights that’ll get you to Santiago in just hour(s) and mins, too.   

Snap up great deals on flights to Santiago from Mexico City 

Choose from flights a day on average, with prices starting at and rising to depending on the cabin class, travel dates, and airline carrier. And if you’re up for a last-minute getaway, you can get great deals on flights from Mexico City to Santiago today!  

Find cheap airfares to Santiago from Mexico City 

Here are our insider tips for bagging a flight bargain: 

  • Look for midweek flights and late night, early morning arrival and departure times
  • Check out other airports near Mexico City and Santiago
  • Avoid peak season (prices tend to be lower in )
  • Be flexible with your travel dates and you can usually get cheaper options  

Reasons to book your flights to Santiago from Mexico City with Wotif

Wotif is a super-easy way to find the best flight for you to Santiago. Get more bang for your buck on flight and hotel or car rental combos and download the free Wotif app to tap into exclusive deals. Book now with Wotif and have a great flight!

 

Great places to stay after flight from Mexico City to Santiago

Holiday Inn Santiago - Airport Terminal by IHG

Holiday Inn Santiago - Airport Terminal by IHG

4 out of 5
Armando Cortinez Norte 2150 Santiago Region Metropolitana
The price is AU$277 per night from 31 Dec to 1 Jan
AU$277
per night
31 Dec - 1 Jan
Stay at this ski hotel in Santiago. Enjoy free Wi-Fi, free parking and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in their ...
8.8/10 Excellent! (1,417 reviews)
The hotel is inside the airport, good for one night stay on transit

Reviewed on 20 Dec 2025

Holiday Inn Santiago - Airport Terminal by IHG
Wyndham Santiago Aeropuerto

Wyndham Santiago Aeropuerto

4.5 out of 5
Av. Americo Vespucio 1284 Santiago Santiago
The price is AU$157 per night from 30 Dec to 31 Dec
AU$157
per night
30 Dec - 31 Dec
Stay at this luxury hotel in Santiago. Enjoy free Wi-Fi, free parking and a full-service spa. Our guests praise the helpful staff and the clean rooms in their ...
9/10 Wonderful! (1,144 reviews)
The staff was great and the hotel very clean. The complementary airport shuttle was amazing.

Reviewed on 20 Dec 2025

Wyndham Santiago Aeropuerto
City Express by Marriott Santiago Aeropuerto Chile

City Express by Marriott Santiago Aeropuerto Chile

3 out of 5
Av. Américo Vespucio Oriente 1295 Santiago
The price is AU$135 per night from 1 Jan to 2 Jan
AU$135
per night
1 Jan - 2 Jan
Stay at this business-friendly hotel in Santiago. Enjoy free breakfast, a free airport shuttle and 24-hour room service. Our guests praise the breakfast and ...
8.6/10 Excellent! (1,004 reviews)
Convenient to airport

Reviewed on 20 Dec 2025

City Express by Marriott Santiago Aeropuerto Chile
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings made with Flight + Hotel on Wotif.com from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.