Extended Stay America - accommodation in Otay Mesa
More than just hotels
Apartments, cabins, holiday rentals and more, plus millions of reviews from Aussie & Kiwi travellers
Flexibility matters
24/7 support, so you can book with confidence
Unlock member prices with Mates Rates
You could save 10% or more on over 100,000 hotels right now.
Check hotel availability in Otay Mesa
Extended Stay America Accommodation in Otay Mesa
Search for hotels in Otay Mesa on Wotif. You can easily find your hotels in Otay Mesa using one of the methods below:
- View our selection of featured hotels in Otay Mesa
- Use the map to find hotels in the Otay Mesa neighbourhood you prefer
- Use the filters to see hotels in a specific area of Otay Mesa, select a specific theme, brand, or hotel class from basic to luxury hotels in Otay Mesa
- Enter your travel dates to view the best deals on hotels in Otay Mesa - while they last
New reviews! Best hotels in Otay Mesa
Wotif Verified Review
5 / 5
Weekend getaway at this beautiful property was just what i needed defiantly will recommend 10/10
A verified traveller stayed at Legacy Resort Hotel & Spa
Posted 6 hours ago
More Destinations
- Hyatt Hotels in Temecula
- Downtown San Diego Hotels
- Hotels near Petco Park
- Hotels with Balconies in Gaslamp Quarter
- Gaslamp Quarter Hotels
- Casa de Oro-Mount Helix Hotels
- South Park Hotels
- Casino Hotels in San Ysidro
- San Ysidro Hotels
- Bartell Hotels in San Diego
- Best Western Hotels in San Diego
- Cheap Hotels in San Diego
- Family Hotels in San Diego
- Hotels with Suites in San Diego
- Independent Hotels in San Diego
- Ksl Resorts in San Diego
- La Quinta Inn & Suites Hotels in San Diego
- Loews Hotels in San Diego
- Luxury Hotels in San Diego
- Motel 6 Hotels in San Diego
- Noble House Hotels in San Diego
- Wyndham Hotels in San Diego
- San Diego Hotels
- Houseboats in San Diego
- La Quinta Inn & Suites Hotels in Fallbrook
- Apartment Hotels in San Diego County
- Golf Hotels in San Diego County
- Hotels with a Waterpark in San Diego County
- Winery Hotels in San Diego County
- San Diego County Hotels
- Farmstay in San Diego County
- Cabin Rentals in San Diego County
- Caravan Parks in San Diego County
- Guest Houses in San Diego County
- Hostels in San Diego County
- Hotels near San Diego Convention Center
- La Mesa Hotels
- Hyatt Hotels in Cardiff-by-the-Sea
- Cabin Rentals in Chula Vista
- Hostels in Chula Vista
- Apartment Hotels in Chula Vista
- Family Hotels in Chula Vista
- Hotels with Hot Tubs in Chula Vista
- Hotels near Len Moore Skate Park
- Hotels near Brown Field Municipal
- Marriott Hotels & Resorts in Ramona
- Hyatt Hotels in Escondido
- Best Western Hotels in Julian
- National City Hotels
- Hotels near Mount Helix Park
- La Quinta Inn & Suites Hotels in Murrieta
- Motel 6 Hotels in Murrieta
- Wyndham Hotels in Murrieta
- Hotels near The Salvation Army Kroc Center
- Extended Stay America Hotels in Catalina Island
- Hilton Hotels in Catalina Island
- Hyatt Hotels in Catalina Island
- Marriott Hotels & Resorts in Catalina Island
- Lemon Grove Hotels
- Hotels near Coronado Beach
- Hilton Hotels in San Juan Capistrano
- Wyndham Hotels in Coronado Island
- Best Western Hotels in Ocotillo
- Marriott Hotels & Resorts in Ladera Ranch
- Four Seasons Hotels in Carlsbad
- Imperial Beach Hotels
- Beach Hotels in Coronado
- Cheap Hotels in Coronado
- Family Hotels in Coronado
- Hotels with Air Conditioning in Coronado
- Hotels with Hot Tubs in Coronado
- Hotels with a Wedding Venue in Coronado
- Coronado Hotels
- Bonita Hotels
- Marriott Hotels & Resorts in Wildomar
- Hotels near Chula Vista Elite Athlete Training Center
- Accor Hotels in San Clemente
- La Quinta Inn & Suites Hotels in San Clemente
- Motel 6 Hotels in Spring Valley
- Spring Valley Hotels
- Hyatt Hotels in Dana Point
- East Village Hotels
- La Quinta Inn & Suites Hotels in El Cajon
- Golden Hill Hotels
- Hilton Hotels in Borrego Springs
^Eligibility requirements and conditions apply.