Extended Stay America - accommodation in Otay Mesa

More than just hotels
Apartments, cabins, holiday rentals and more, plus millions of reviews from Aussie & Kiwi travellers

Flexibility matters
24/7 support, so you can book with confidence

Unlock member prices with Mates Rates
You could save 10% or more on over 100,000 hotels right now.

Check hotel availability in Otay Mesa

Tonight
Check prices in Otay Mesa for tonight, 8 July - 9 July
8 July - 9 July
Tomorrow night
Check prices in Otay Mesa for tomorrow night, 9 July - 10 July
9 July - 10 July
This weekend
Check prices in Otay Mesa for this weekend, 11 July - 13 July
11 July - 13 July
Next weekend
Check prices in Otay Mesa for next weekend, 18 July - 20 July
18 July - 20 July

Extended Stay America Accommodation in Otay Mesa

Search for hotels in Otay Mesa on Wotif. You can easily find your hotels in Otay Mesa using one of the methods below:

  • View our selection of featured hotels in Otay Mesa
  • Use the map to find hotels in the Otay Mesa neighbourhood you prefer
  • Use the filters to see hotels in a specific area of Otay Mesa, select a specific theme, brand, or hotel class from basic to luxury hotels in Otay Mesa
  • Enter your travel dates to view the best deals on hotels in Otay Mesa - while they last

New reviews! Best hotels in Otay Mesa

Marriott Marquis San Diego Marina
Overall Great Stay
5 / 5
Stayed for the 4th of July weekend. Very crowded but was expected. Elevators run really slow which did not make the crowds easy to deal with. Other than that it was a great stay.
A verified traveller stayed at Marriott Marquis San Diego Marina
Posted 2 days ago
Marriott Marquis San Diego Marina

Neighbourhoods

Nearby cities

Near an airport

Near an Attraction

Hotel themes

Hotel brands

^Eligibility requirements and conditions apply.