Defiance Holiday Packages

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Don't fritter away your precious cash! Be a sensible spender with Wotif.

Our neat little packages combine your hotels and flights to make travelling a breeze.

With the extra money you can see even more in Defiance.

Your savings could add up to if you lock in a package. And how do you do this? Just mix and match from more than 550 airlines and 665,000 properties.

Wotif has some of the most competitive prices anywhere online. Better start packing your bags — now's the ideal time to hit the skies.

Car Hire in Defiance

If you're hoping to hire a vehicle from Spirit of St. Louis Airport, we suggest Budget (801 Spirit Of St. Louis Blvd) or Avis (801 Spirit of St Louis Blvd). They're just a short taxi ride from the terminal.

There's no point stressing about car rental companies in the very centre of the city when the neighbourhood of O'Fallon has a bunch. Explore the sweet deals at Enterprise (1491 Mexico Loop Rd E), or pop by Budget (2721 Hwy K) and explore their offerings.

Holidays to Defiance

Before you wave goodbye to the cat and jump in that taxi to the airport, it's not a bad idea to know the basics about where you're travelling to. Keep reading for a few helpful Defiance pointers.

If you're busting to experience another side of the significant city of St. Louis, staying in Defiance is a ripper of an idea. From the city centre, the neighbourhood is 50 kilometres away to the west.

Solo adventurers won't be by themselves for long in Defiance. With St. Louis' population standing at around 320 000, you'll definitely make stacks of new friends while you're here.

Top Defiance hotels

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

4.5 out of 5
1 Ameristar Blvd St. Charles MO
Fully refundableReserve now, pay when you stay
The price is AU$295 per night from 24 Nov to 25 Nov
AU$295
24 Nov - 25 Nov
includes taxes & fees
Ameristar Casino Resort and Spa: Luxury hotel with an outdoor pool and 6 restaurants. Located in the city centre.
"We were here for a wedding. Our room was very nice but my son’s bathroom was disgusting and not clean, they had to switch rooms and the only compensation they gave them was a food voucher. Not acceptable with blood and vomit not cleaned from previous guest. We expected more for this caliber of ..."

Reviewed on 8 Nov 2026

Opens in a new windowAmeristar Casino Resort and Spa
Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield

3 out of 5
15431 Conway Rd Chesterfield MO
Fully refundableReserve now, pay when you stay
The price is AU$155 per night from 11 Nov to 12 Nov
AU$155
11 Nov - 12 Nov
includes taxes & fees
Sonesta ES Suites St. Louis - Chesterfield: Pet-friendly hotel with free breakfast and free WiFi. Located in the suburbs.
"The doir had a gap that hardly let us lock it. A pan was put in the cupboard without being washed. The glass sliding door had not been wash from what i believe was dog smears all over it. Under coach was an empty wrapper from mcdonalds. And last ...gasket on freezer door fell off whenever you opened ..."

Reviewed on 9 Nov 2026

Opens in a new windowSonesta ES Suites St. Louis - Chesterfield
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

3.5 out of 5
777 Casino Center Drive Maryland Heights MO
Fully refundableReserve now, pay when you stay
The price is AU$140 per night from 6 Dec to 7 Dec
AU$140
6 Dec - 7 Dec
includes taxes & fees
Hollywood Casino & Hotel St. Louis: Business-friendly hotel with free parking and 7 restaurants. Located near the airport.
Opens in a new windowHollywood Casino & Hotel St. Louis
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.