Flights from Mexico City (MEX) to Santiago (SCL)

Change your flight without a fee on select flights

Money Saving Bundle when you purchase Hotel + Flight! 

Get mobile alerts about flight delays, gate changes and more with the FREE Wotif app

Cheapest Flights from Mexico City (MEX) to Santiago (SCL)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
avianca
avianca
Aeromexico
Copa

Mexico City to Santiago Flight Information

Find the Cheapest Flights from Mexico City (MEX) to Santiago (SCL)

Work hard, travel harder! Wotif brings you the cheapest Mexico City to Santiago flights, making it possible to have a five star holiday without that five star price tag. Browse and compare our top MEX to SCL routes and airport options. So, go ahead and treat yourself, your sweetheart, or the kids to an unforgettable holiday this year.

to Information

Traveling From
Mexico City Intl.
Origin Airport
Origin Airport IATA Code
MEX
Traveling To
Arturo Merino Benitez
Destination Airport
Destination Airport IATA Code
SCL
Number of Airlines Serving
Average Flight Time
hours mins
Direct Flight Time
hours mins
Flight Price
AU$941
Address:
Santiago ,
Chile
IATA code:
SCL
Longitude:
-70.793821
Latitude:
-33.397175
Time zone:
America/Santiago
Address:
Mexico City ,
Mexico
IATA code:
MEX
Longitude:
-99.072778
Latitude:
19.435278
Time zone:
America/Mexico_City

Mexico City to Santiago Flight Deals from AU$941

Considering a quick trip to Santiago, but not sure which is the best route for you? Well, you’re in luck! Wotif has done the hard work, so all you need to do is check out these flights from MEX to SCL. With heaps of cheap fares from Mexico City, we guarantee you’ll be arriving to your holiday destination in style without emptying your bank account in the process.

It’s easy to book flights to Santiago from Mexico City  

For a huge choice of flights, simply enter your travel dates and hit search and we’ll hunt out fantastic deals on one-way, return and multi-city airfares to Santiago from Mexico City from 10 different airlines. If you click the ‘direct flights’ box, you see flights that’ll get you to Santiago in just hour(s) and mins, too.   

Snap up great deals on flights to Santiago from Mexico City 

Choose from flights a day on average, with prices starting at AU$941 and rising to AU$1,122 depending on the cabin class, travel dates, and airline carrier. And if you’re up for a last-minute getaway, you can get great deals on flights from Mexico City to Santiago today!  

Find cheap airfares to Santiago from Mexico City 

Here are our insider tips for bagging a flight bargain: 

  • Look for midweek flights and late night, early morning arrival and departure times
  • Check out other airports near Mexico City and Santiago
  • Avoid peak season (prices tend to be lower in February)
  • Be flexible with your travel dates and you can usually get cheaper options  

Reasons to book your flights to Santiago from Mexico City with Wotif

Wotif is a super-easy way to find the best flight for you to Santiago. Get more bang for your buck on flight and hotel or car rental combos and download the free Wotif app to tap into exclusive deals. Book now with Wotif and have a great flight!

 

Great places to stay after flight from Mexico City to Santiago

Holiday Inn Santiago - Airport Terminal by IHG
Holiday Inn Santiago - Airport Terminal by IHG
4 out of 5
Armando Cortinez Norte 2150, Santiago, Region Metropolitana
The price is AU$223 per night from 14 May to 15 May
AU$223
14 May - 15 May
Stay at this 4-star ski hotel in Santiago. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the restaurant and the helpful staff in ...
8.8/10 Excellent! (1,227 reviews)
"Hotel personnel is great. Old premises. Should have a direct connection with T2 international internally within the hotel, that should be good, especially in very early hours or very late in the evening. Also, breakfast is expensive, should be different choices if we want few items to eat/drink instead ..."

Reviewed on 3 May 2025

Holiday Inn Santiago - Airport Terminal by IHG
City Express by Marriott Santiago Aeropuerto Chile
City Express by Marriott Santiago Aeropuerto Chile
3 out of 5
Av. Américo Vespucio Oriente 1295, Pudahuel, Santiago
The price is AU$133 per night from 10 May to 11 May
AU$133
10 May - 11 May
Stay at this 3-star business-friendly hotel in Santiago. Enjoy free breakfast, a free airport shuttle, and 24-hour room service. Our guests praise the breakfast ...
8.8/10 Excellent! (1,001 reviews)
"Great"

Reviewed on 20 Apr. 2025

City Express by Marriott Santiago Aeropuerto Chile
La Quinta by Wyndham Santiago Aeropuerto
La Quinta by Wyndham Santiago Aeropuerto
4 out of 5
Av. Americo Vespucio 1284, Santiago, Santiago
The price is AU$177 per night from 8 May to 9 May
AU$177
8 May - 9 May
Stay at this 4-star spa hotel in Santiago. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (1,002 reviews)
"Perfect for a transit stay in Santiago, close to the airport."

Reviewed on 6 May 2025

La Quinta by Wyndham Santiago Aeropuerto
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

^Savings based on all package bookings made with Flight + Hotel on Wotif.com from , as compared to the price of the same components booked separately. Savings will vary based on origin/destination, length of trip, stay dates and selected travel supplier(s). Savings not available on all packages.