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Comfort Inn & Suites Sikeston I-55

2.5 star property
Hotel in Sikeston with indoor pool and fitness centre

Photo gallery for Comfort Inn & Suites Sikeston I-55

Exterior
Desk, free WiFi, bed sheets, alarm clocks
Desk, free WiFi, bed sheets, alarm clocks
Lobby
Indoor pool

Reviews

8.4 out of 10
Very good

Popular amenities

  • Pet-friendly
  • Parking included
  • Free Wi-Fi
  • Air-conditioning
  • Gym
The current price is AU$138
includes taxes & fees
8 Feb - 9 Feb

Explore the area

View map
109 Matthews Ln, Sikeston, MO, 63801
  • Place, City of Miner Convention Center
    ‪5 min walk‬
  • Place, Isle Casino Cape Girardeau
    ‪33 min drive‬
  • Place, Southeast Missouri State University
    ‪33 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪24 min drive‬

Room options

View all photos for Standard Room, 2 Queen Beds, Non Smoking

Standard Room, 2 Queen Beds, Non Smoking

Standard Room, 2 Queen Beds, Non Smoking

8.0 out of 10
Very good
(11 reviews)

Highlights

Air conditioning
Fridge
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking

Highlights

Air conditioning
Fridge
Separate bedroom
Sofa bed
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Room, 1 King Bed, Accessible, Non Smoking

Room, 1 King Bed, Accessible, Non Smoking

Room, 1 King Bed, Accessible, Non Smoking

9.0 out of 10
Wonderful
(2 reviews)

Highlights

Air conditioning
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

Room, 2 Queen Beds, Accessible, Non Smoking

Room, 2 Queen Beds, Accessible, Non Smoking

10.0 out of 10
Exceptional
(4 reviews)

Highlights

Air conditioning
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 4
  • 2 Queen Beds

View all photos for Standard Room, 1 King Bed, Non Smoking

Standard Room, 1 King Bed, Non Smoking

Standard Room, 1 King Bed, Non Smoking

8.0 out of 10
Very good
(14 reviews)

Highlights

Air conditioning
Fridge
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 2
  • 1 King Bed

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Best Western Plus Sikeston I-55

Sikeston
  • Pool
  • Breakfast included
  • Pet-friendly
  • Parking included
4.2 out of 5, Very good, 1,005 reviews
The price is AU$132
includes taxes & fees
15 Feb - 16 Feb
Best Western Plus Sikeston I-55

About the area

Sikeston

At Comfort Inn & Suites Sikeston I-55, you'll be 0.6 km (0.4 mi) from City of Miner Convention Center and 5.2 km (3.3 mi) from Sikeston Depot Museum. Highlights at this hotel include an indoor swimming pool and in-room free WiFi. .This business-friendly hotel offers free WiFi in public areas, a fitness centre and a business centre. Added amenities include laundry facilities, a 24-hour front desk and a front desk safe. There's also the convenience of free self parking. .Sights within a 20-minute drive of this Sikeston hotel include Central Park and Front Street Studio & Art Gallery.

What's nearby

  • City of Miner Convention Center - 5 min walk - 0.4 km
  • Sikeston Depot Museum - 5 min drive - 4.8 km
  • Saint Francis Medical Center - 28 min drive - 57.8 km
  • Isle Casino Cape Girardeau - 33 min drive - 61.2 km
  • Southeast Missouri State University - 33 min drive - 62.0 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 29 min drive

Restaurants

  • ‪Lambert's Cafe - ‬17 min walk
  • ‪Buffalo Wild Wings - ‬5 min drive
  • ‪Burger King - ‬4 min drive
  • ‪Starbucks - ‬6 min drive
  • ‪McDonald's - ‬2 min walk

About this property

Comfort Inn & Suites Sikeston I-55

Hotel in Sikeston with indoor pool and fitness centre
Comfort Inn & Suites Sikeston I-55 offers its guests an indoor pool and a fitness centre. WiFi is free in public spaces. There's an onsite business centre. The business-friendly Comfort Inn & Suites Sikeston I-55 also features laundry facilities, a front desk safe, and a lift. Self parking is free.
  • 64 guestrooms or units
  • 3 levels
  • Business facilities
  • Self-service laundry
  • Front desk (24 hours)
  • Front desk safe
  • Lift
Comfort Inn & Suites Sikeston I-55 offers 64 air-conditioned accommodations, with coffee/tea makers. Guests can surf the web using complimentary wireless Internet access.

Bathrooms include baths or showers. Business-friendly amenities include desks and telephones.

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Free daily full breakfast
Best Western Plus Sikeston I-55
  • Pool
  • Breakfast included
  • Pet-friendly
  • Parking included
4.2 out of 5, Very good, 1,005 reviews
The price is AU$132
includes taxes & fees
8 Feb - 9 Feb
Best Western Plus Sikeston I-55

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Free self parking on site
  • Limited on-site self parking
  • Wheelchair-accessible parking available

Things to do

  • Gym
  • Indoor pool

Family friendly

  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Safe at front desk

Business services

  • Business centre

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Lift
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible registration desk

More

  • 3 floors
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Bathtub or shower
  • Private bathroom
  • Towels provided

Entertainment

  • Cable/satellite channels

Food and drink

  • Coffee/tea maker

More

  • Air conditioning
  • Desk
  • Phone

Policies

Check-in

Check-in start time: 2:00 PM; check-in end time: anytime
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 20 per pet, per night
  • Only dogs and cats are allowed
  • Maximum 2 (weight limit: 20 lb per pet)
  • Certain rooms only
  • You can request a pet-friendly room by reaching out to the property at the number on the booking confirmation
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Pet fee: USD 20 per pet, per night
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, American Express, Discover, JCB International and Carte Blanche. Cash is not accepted. This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice) guidelines.

We should mention

  • Pets are welcome in specific rooms only, which can be requested by contacting the property directly at the number on your booking confirmation (please see the Fees section for related charges).

Property is also known as

Comfort Inn Sikeston Hotel
Comfort Inn Sikeston

Frequently asked questions

What is the cancellation policy at Comfort Inn & Suites Sikeston I-55?

Comfort Inn & Suites Sikeston I-55 offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at Comfort Inn & Suites Sikeston I-55?

As of 30 Jan 2026, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Sikeston I-55 on 8 Feb 2026 start from AU$138.25, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at Comfort Inn & Suites Sikeston I-55?

Yep, Comfort Inn & Suites Sikeston I-55 has a free self car park.

Does Comfort Inn & Suites Sikeston I-55 have a pool?

Comfort Inn & Suites Sikeston I-55 has an indoor pool.

Is there a free airport shuttle available at Comfort Inn & Suites Sikeston I-55?

No, Comfort Inn & Suites Sikeston I-55 does not offer an airport shuttle service.

What time are check-in & check-out at Comfort Inn & Suites Sikeston I-55?

Check-in begins at 2:00 PM. Check-out time is 11:00 AM.

Comfort Inn & Suites Sikeston I-55 Reviews

Reviews

8.4

Very good

Rating 10 - Excellent. 135 out of 286 reviews
Rating 8 - Good. 94 out of 286 reviews
Rating 6 - Okay. 29 out of 286 reviews
Rating 4 - Poor. 19 out of 286 reviews
Rating 2 - Terrible. 9 out of 286 reviews

8.6/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.2/10

Property conditions & facilities

Reviews

10/10 Excellent

Shonta', Jacksonville

Liked: Cleanliness, staff & service, property conditions & facilities
Love Everything
Stayed 4 nights in Oct 2025

10/10 Excellent

Kimberlee, Oskaloosa

Stayed 1 night in Oct 2025

10/10 Excellent

jacqueline

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It was quiet and peaceful. It was by everything we wanted to go.
Stayed 2 nights in Oct 2025

6/10 Okay

Joan

Liked: Cleanliness, room comfort
Stayed 1 night in Oct 2025

10/10 Excellent

Shonta', Jacksonville

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The Jacuzzi was the Best!!! 👏
Stayed 6 nights in Oct 2025

2/10 Terrible

samuel

Business traveller
Disliked: Cleanliness, property conditions & facilities
Not a very good hotel will not stay there again
Stayed 1 night in Jul 2025

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It was a very nice stay. The pool was clean and enjoying!
Stayed 1 night in Jul 2025

10/10 Excellent

Antonio

Stayed 1 night in Jul 2025

8/10 Good

Juanita

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 3 nights in Jun 2025

6/10 Okay

Juanita

Travelled with family
Liked: Cleanliness, amenities, property conditions & facilities
The check in guy threw my id at me and was rude
Stayed 3 nights in Jun 2025

4/10 Poor

Latrisha, Kalamazoo

Travelled with partner
Disliked: Cleanliness, amenities, property conditions & facilities
Pet hair all iver the chair in the room. Specs of poop on toilet seat. Ironing board filthy. Linens torn. Lumpy pillows. Distinct smell of room a mnd hallway stairs. Side doors not secure. Holes in closet door. Freezer portion of fridge was dirty. Watery powdered eggs and hard biscuits. Had to purchase clorox cleaning wipes to wipe down everything, went through entire bottle. Used entire bottle of febreeze. First stay was okay. Last couple has been terrible, but price of rooms increased. Lady at front desk was nice was about all i liked about sleeping there. Last stay at Comfort Inn as it's not worth the price.
Stayed 2 nights in Jun 2025

6/10 Okay

Wendy

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Everything was good. The beds were too hard and pillows were too soft.
Stayed 1 night in Jun 2025

10/10 Excellent

Corinthian

Liked: Cleanliness, amenities, property conditions & facilities
It was cool
Stayed 3 nights in May 2025

8/10 Good

Sidney

Stayed 1 night in Jun 2025

8/10 Good

George

Travelled with family
Liked: Cleanliness, amenities, property conditions & facilities
Clean
Stayed 1 night in Jun 2025

10/10 Excellent

Francis

Stayed 1 night in Jun 2025

4/10 Poor

Elmarie

Liked: Property conditions & facilities
Had a barking dog next door. Had to work on heater the knob was messed up. Had to call for someone to come fix tv and it still never worked the best
Stayed 1 night in May 2025

6/10 Okay

Latrisha, Kalamazoo

Travelled with partner
Disliked: Cleanliness
Toilet did not flush. Heard water dripping from shower all night. Had to request a different room. Beds were comfortable. Furniture can use cleaning/dusting. Freezer had something wasted in it. Staff was friendly at the front desk.
Stayed 2 nights in Apr 2025

8/10 Good

David

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in May 2025

8/10 Good

Patricia, Richmond

Stayed 1 night in May 2025

10/10 Excellent

Peggy

Liked: Cleanliness, staff & service, property conditions & facilities
The facility was very nice.
Stayed 2 nights in May 2025

10/10 Excellent

Timothy, Hartford

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean & friendly service. Easy access from the highway. Bed is comfortable. Breakfast area looks very nice. A good selection of food choices. Would recommend this property. The ice machine wasn’t working on our floor, but could get ice near the lobby, so not a huge issue.
Stayed 1 night in May 2025

8/10 Good

John

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good stay

It was decent…slept well The room was clean
Stayed 1 night in May 2025

8/10 Good

Luther

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Feb 2025

10/10 Excellent

Sharon

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice
Stayed 1 night in Apr 2025