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Comfort Inn & Suites Sikeston I-55

2.5 star property
Hotel in Sikeston with fitness centre and 24-hour front desk

Photo gallery for Comfort Inn & Suites Sikeston I-55

Exterior
Lobby
Room, 2 Queen Beds, Accessible, Non Smoking
Meeting facility
Breakfast area

Reviews

8.4 out of 10
Very good

Popular amenities

  • Gym
  • Laundry
  • Pet-friendly
  • Parking included
  • Free WiFi
The current price is AU$144
includes taxes & fees
31 Dec - 1 Jan 2026

Explore the area

View map
109 Matthews Ln, Sikeston, MO, 63801
  • Place, City of Miner Convention Center
    ‪5 min walk‬
  • Place, Isle Casino Cape Girardeau
    ‪33 min drive‬
  • Place, Southeast Missouri State University
    ‪33 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪24 min drive‬

Room options

View all photos for Standard Room, 2 Queen Beds, Non Smoking

Standard Room, 2 Queen Beds, Non Smoking

Standard Room, 2 Queen Beds, Non Smoking

8.0 out of 10
Very good
(11 reviews)

Highlights

Air conditioning
Fridge
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 4
  • 2 Queen Beds

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking

Highlights

Air conditioning
Fridge
Sofa bed
Separate bedroom
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • 1 bedroom
  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed

View all photos for Room, 1 King Bed, Accessible, Non Smoking

Room, 1 King Bed, Accessible, Non Smoking

Room, 1 King Bed, Accessible, Non Smoking

9.0 out of 10
Wonderful
(2 reviews)

Highlights

Air conditioning
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

Room, 2 Queen Beds, Accessible, Non Smoking

Room, 2 Queen Beds, Accessible, Non Smoking

10.0 out of 10
Exceptional
(4 reviews)

Highlights

Air conditioning
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 4
  • 2 Queen Beds

View all photos for Standard Room, 1 King Bed, Non Smoking

Standard Room, 1 King Bed, Non Smoking

Standard Room, 1 King Bed, Non Smoking

8.0 out of 10
Very good
(14 reviews)

Highlights

Air conditioning
Fridge
Private bathroom
Coffee/tea maker
Cable/satellite channels
Desk
  • Sleeps 2
  • 1 King Bed

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    About the area

    Sikeston

    At Comfort Inn & Suites Sikeston I-55, you'll be 0.6 km (0.4 mi) from City of Miner Convention Center and 5.2 km (3.3 mi) from Sikeston Depot Museum. Highlights at this hotel include an indoor swimming pool and in-room free WiFi. .This business-friendly hotel offers free WiFi in public areas, a fitness centre and a business centre. Added amenities include laundry facilities, a 24-hour front desk and a front desk safe. There's also the convenience of free self parking. .Sights within a 20-minute drive of this Sikeston hotel include Central Park and Front Street Studio & Art Gallery.

    What's nearby

    • City of Miner Convention Center - 5 min walk - 0.4 km
    • Saint Francis Medical Center - 28 min drive - 57.8 km
    • Isle Casino Cape Girardeau - 33 min drive - 61.2 km
    • Southeast Missouri State University - 33 min drive - 62.0 km
    • Show Me Center - 34 min drive - 62.9 km

    Getting around

    • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 29 min drive

    Restaurants

    • ‪Lambert's Cafe - ‬17 min walk
    • ‪Buffalo Wild Wings - ‬5 min drive
    • ‪Pizza Inn - ‬2 min drive
    • ‪Burger King - ‬4 min drive
    • ‪McDonald's - ‬2 min walk

    About this property

    Comfort Inn & Suites Sikeston I-55

    Hotel in Sikeston with fitness centre and 24-hour front desk
    Comfort Inn & Suites Sikeston I-55 offers its guests an indoor pool and a fitness centre. WiFi is free in public spaces. There's an onsite business centre. The business-friendly Comfort Inn & Suites Sikeston I-55 also features laundry facilities, a front desk safe, and a lift. Self parking is free.
    • 64 guestrooms or units
    • 3 levels
    • Business facilities
    • Self-service laundry
    • Front desk (24 hours)
    • Front desk safe
    • Lift
    Comfort Inn & Suites Sikeston I-55 offers 64 air-conditioned accommodations, with coffee/tea makers. Guests can surf the web using complimentary wireless Internet access.

    Bathrooms include baths or showers. Business-friendly amenities include desks and telephones.

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    Property amenities

    Internet

    • Available in all rooms: Free WiFi
    • Available in some public areas: Free WiFi

    Parking and transport

    • Free self parking on site
    • Wheelchair-accessible parking available

    Things to do

    • Gym
    • Indoor pool

    Family friendly

    • Indoor pool
    • Laundry facilities

    Conveniences

    • 24-hour front desk
    • Laundry facilities
    • Safe at front desk

    Business services

    • Business centre

    Accessibility

    • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
    • Lift
    • Wheelchair accessible (may have limitations)
    • Wheelchair-accessible parking
    • Wheelchair-accessible registration desk

    More

    • 3 floors
    • Smoke-free property

    Room amenities

    Bedroom

    • Bedsheets provided

    Bathroom

    • Bathtub or shower
    • Private bathroom
    • Towels provided

    Entertainment

    • Cable/satellite channels

    Food and drink

    • Coffee/tea maker

    More

    • Air conditioning
    • Desk
    • Phone

    Policies

    Check-in

    Check-in start time: 2:00 PM; check-in end time: anytime
    Minimum check-in age - 21

    Check-out

    Check-out before 11:00 AM

    Special check-in instructions

    Front desk staff will greet guests on arrival at the property
    Information provided by the property may be translated using automated translation tools

    Access methods

    Staffed front desk

    Pets

    • Pets: USD 20 per pet, per night
    • Only dogs and cats are allowed
    • Maximum 2 (weight limit: 20 lb per pet)
    • Certain rooms only
    • You can request a pet-friendly room by reaching out to the property at the number on the booking confirmation
      • Service animals are exempt from fees.

    Children and extra beds

    • Children are welcome.
    • Rollaway/extra beds are not available.
    • Cots (infant beds) are not available.

    Payment types

    Important information

    Optional extras

    The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

    • Pet fee: USD 20 per pet, per night
    • Service animals are exempt from fees

    This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

    You need to know

    Extra-person charges may apply and vary depending on property policy
    Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
    Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
    This property accepts credit cards; cash is not accepted
    This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
    Charges for extra guests may apply and vary according to property policy.
    A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
    Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
      This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, American Express, Discover, JCB International and Carte Blanche. Cash is not accepted. This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice) guidelines.

    We should mention

    • Pets are welcome in specific rooms only, which can be requested by contacting the property directly at the number on your booking confirmation (please see the Fees section for related charges).

    Property is also known as

    Comfort Inn Sikeston Hotel
    Comfort Inn Sikeston

    Frequently asked questions

    What is the cancellation policy at Comfort Inn & Suites Sikeston I-55?

    Comfort Inn & Suites Sikeston I-55 offers free cancellation on select room rates. Check out the cancellation policy for more info.

    How much does it cost to stay at Comfort Inn & Suites Sikeston I-55?

    As of 13 Dec 2025, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Sikeston I-55 on 31 Dec 2025 start from AU$143.97, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

    Is parking available at Comfort Inn & Suites Sikeston I-55?

    Yep, Comfort Inn & Suites Sikeston I-55 has a free self car park.

    Does Comfort Inn & Suites Sikeston I-55 have a pool?

    Comfort Inn & Suites Sikeston I-55 has an indoor pool.

    Is there a free airport shuttle available at Comfort Inn & Suites Sikeston I-55?

    No, Comfort Inn & Suites Sikeston I-55 does not offer an airport shuttle service.

    What time are check-in & check-out at Comfort Inn & Suites Sikeston I-55?

    Check-in begins at 2:00 PM. Check-out time is 11:00 AM.

    Comfort Inn & Suites Sikeston I-55 Reviews

    Reviews

    8.4

    Very good

    Rating 10 - Excellent. 132 out of 282 reviews
    Rating 8 - Good. 93 out of 282 reviews
    Rating 6 - Okay. 29 out of 282 reviews
    Rating 4 - Poor. 19 out of 282 reviews
    Rating 2 - Terrible. 9 out of 282 reviews

    8.6/10

    Cleanliness

    8.8/10

    Staff & service

    8.2/10

    Amenities

    8.2/10

    Property conditions & facilities

    8.2/10

    Eco-friendliness

    Reviews

    2/10 Terrible

    samuel

    Business traveller
    Disliked: Cleanliness, property conditions & facilities
    Not a very good hotel will not stay there again
    Stayed 1 night in Jul 2025

    10/10 Excellent

    Lisa

    Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
    It was a very nice stay. The pool was clean and enjoying!
    Stayed 1 night in Jul 2025

    10/10 Excellent

    Antonio

    Stayed 1 night in Jul 2025

    8/10 Good

    Juanita

    Travelled with family
    Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
    Stayed 3 nights in Jun 2025

    6/10 Okay

    Juanita

    Travelled with family
    Liked: Cleanliness, amenities, property conditions & facilities
    The check in guy threw my id at me and was rude
    Stayed 3 nights in Jun 2025

    4/10 Poor

    Latrisha, Kalamazoo

    Travelled with partner
    Disliked: Cleanliness, amenities, property conditions & facilities
    Pet hair all iver the chair in the room. Specs of poop on toilet seat. Ironing board filthy. Linens torn. Lumpy pillows. Distinct smell of room a mnd hallway stairs. Side doors not secure. Holes in closet door. Freezer portion of fridge was dirty. Watery powdered eggs and hard biscuits. Had to purchase clorox cleaning wipes to wipe down everything, went through entire bottle. Used entire bottle of febreeze. First stay was okay. Last couple has been terrible, but price of rooms increased. Lady at front desk was nice was about all i liked about sleeping there. Last stay at Comfort Inn as it's not worth the price.
    Stayed 2 nights in Jun 2025

    6/10 Okay

    Wendy

    Travelled with family
    Liked: Cleanliness, staff & service, property conditions & facilities
    Everything was good. The beds were too hard and pillows were too soft.
    Stayed 1 night in Jun 2025

    10/10 Excellent

    Corinthian

    Liked: Cleanliness, amenities, property conditions & facilities
    It was cool
    Stayed 3 nights in May 2025

    8/10 Good

    Sidney

    Stayed 1 night in Jun 2025

    8/10 Good

    George

    Travelled with family
    Liked: Cleanliness, amenities, property conditions & facilities
    Clean
    Stayed 1 night in Jun 2025

    10/10 Excellent

    Francis

    Stayed 1 night in Jun 2025

    4/10 Poor

    Elmarie

    Liked: Property conditions & facilities
    Had a barking dog next door. Had to work on heater the knob was messed up. Had to call for someone to come fix tv and it still never worked the best
    Stayed 1 night in May 2025

    6/10 Okay

    Latrisha, Kalamazoo

    Travelled with partner
    Disliked: Cleanliness
    Toilet did not flush. Heard water dripping from shower all night. Had to request a different room. Beds were comfortable. Furniture can use cleaning/dusting. Freezer had something wasted in it. Staff was friendly at the front desk.
    Stayed 2 nights in Apr 2025

    8/10 Good

    David

    Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
    Stayed 1 night in May 2025

    8/10 Good

    Patricia, Richmond

    Stayed 1 night in May 2025

    10/10 Excellent

    Peggy

    Liked: Cleanliness, staff & service, property conditions & facilities
    The facility was very nice.
    Stayed 2 nights in May 2025

    10/10 Excellent

    Timothy, Hartford

    Travelled with family
    Liked: Cleanliness, staff & service, amenities, property conditions & facilities
    Clean & friendly service. Easy access from the highway. Bed is comfortable. Breakfast area looks very nice. A good selection of food choices. Would recommend this property. The ice machine wasn’t working on our floor, but could get ice near the lobby, so not a huge issue.
    Stayed 1 night in May 2025

    8/10 Good

    John

    Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

    Good stay

    It was decent…slept well The room was clean
    Stayed 1 night in May 2025

    8/10 Good

    Luther

    Travelled with family
    Liked: Cleanliness, staff & service, property conditions & facilities
    Stayed 2 nights in Feb 2025

    10/10 Excellent

    Sharon

    Travelled with partner
    Liked: Cleanliness, staff & service, amenities, property conditions & facilities
    Nice
    Stayed 1 night in Apr 2025

    10/10 Excellent

    Allan

    Liked: Cleanliness, staff & service, property conditions & facilities
    Stayed 1 night in Apr 2025

    10/10 Excellent

    Meaghan

    Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
    Stayed 1 night in Apr 2025

    8/10 Good

    Frank

    Stayed 2 nights in Apr 2025

    10/10 Excellent

    Marsha

    Travelled with partner
    Liked: Cleanliness, staff & service, amenities, property conditions & facilities
    It was okay, quiet and helpful.
    Stayed 1 night in Apr 2025

    8/10 Good

    Sheila a

    Business traveller
    Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

    Quiet

    Clean enough though older. Main thing for me was peace and quiet so I could sleep during the day ( working nights while in town). That was great!
    Stayed 2 nights in Mar 2025