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Comfort Inn & Suites Sikeston I-55

2.5 star property

Photo gallery for Comfort Inn & Suites Sikeston I-55

Exterior
Breakfast area
Desk, free WiFi, bed sheets, alarm clocks
Meeting facility
Lobby

Reviews

8.4 out of 10
Very good

Popular amenities

  • Pet-friendly
  • Parking included
  • Free Wi-Fi
  • Air-conditioning
  • Gym
The current price is AU$157
includes taxes & fees
6 July - 7 July

Explore the area

View map
109 Matthews Ln, Sikeston, MO, 63801
  • Place, City of Miner Convention Center
    ‪5 min walk‬
  • Place, Sikeston Depot Museum
    ‪5 min drive‬
  • Place, Century Casino & Hotel Cape Girardeau
    ‪31 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪22 min drive‬

Room options

View all photos for 1 King Bed, Suite, Nonsmoking

Desk, free WiFi, bed sheets, alarm clocks

1 King Bed, Suite, Nonsmoking

  • Sleeps 2
  • Free Wi-Fi

View all photos for 2 Queen Beds, Nonsmoking, Accessible

Desk, free WiFi, bed sheets, alarm clocks

2 Queen Beds, Nonsmoking, Accessible

  • Sleeps 4
  • Free Wi-Fi

View all photos for 1 King Bed, Nonsmoking, Accessible

Desk, free WiFi, bed sheets, alarm clocks

1 King Bed, Nonsmoking, Accessible

  • Sleeps 2
  • Free Wi-Fi

View all photos for Standard Room, 2 Queen Beds, Non Smoking

Standard Room, 2 Queen Beds, Non Smoking

Standard Room, 2 Queen Beds, Non Smoking

8.0 out of 10
Very good
(13 reviews)
  • 1 bedroom
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking

Suite, 1 King Bed with Sofa bed, Non Smoking

  • 1 bedroom
  • Sleeps 4
  • 1 King Bed and 1 Double Sofa Bed
  • Free Wi-Fi

View all photos for Room, 1 King Bed, Accessible, Non Smoking

Room, 1 King Bed, Accessible, Non Smoking

Room, 1 King Bed, Accessible, Non Smoking

8.6 out of 10
Excellent
(4 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

View all photos for Room, 2 Queen Beds, Accessible, Non Smoking

Room, 2 Queen Beds, Accessible, Non Smoking

Room, 2 Queen Beds, Accessible, Non Smoking

10.0 out of 10
Exceptional
(4 reviews)
  • Sleeps 4
  • 2 Queen Beds
  • Free Wi-Fi

View all photos for Standard Room, 1 King Bed, Non Smoking

Standard Room, 1 King Bed, Non Smoking

Standard Room, 1 King Bed, Non Smoking

8.0 out of 10
Very good
(15 reviews)
  • 1 bedroom
  • Sleeps 2
  • 1 King Bed
  • Free Wi-Fi

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  • Pool
  • Breakfast included
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  • Parking included
4.2 out of 5, Very good, 1,012 reviews
The price is AU$141
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14 July - 15 July
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About the area

Sikeston

At Comfort Inn & Suites Sikeston I-55, you'll be 0.6 km (0.4 mi) from City of Miner Convention Center and 5.2 km (3.3 mi) from Sikeston Depot Museum. Highlights at this hotel include an indoor swimming pool and in-room free WiFi. .This business-friendly hotel offers free WiFi in public areas, a fitness centre and a business centre. Added amenities include laundry facilities, a 24-hour front desk and a front desk safe. There's also the convenience of free self parking. .Sights within a 20-minute drive of this Sikeston hotel include Central Park and Front Street Studio & Art Gallery.

What's nearby

  • City of Miner Convention Center - 5 min walk - 0.4 km
  • Central Park - 4 min drive - 5.9 km
  • Sikeston Depot Museum - 5 min drive - 5.9 km
  • Southeast Missouri State University - 31 min drive - 62.3 km
  • Century Casino & Hotel Cape Girardeau - 31 min drive - 61.5 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 29 min drive

Restaurants

  • ‪Lambert's Cafe - ‬17 min walk
  • ‪Buffalo Wild Wings - ‬5 min drive
  • ‪Burger King - ‬4 min drive
  • ‪Imo's Pizza - ‬6 min drive
  • ‪Starbucks - ‬6 min drive

About this property

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55 offers its guests an indoor pool and a fitness centre. WiFi is free in public spaces. There's an onsite business centre. The business-friendly Comfort Inn & Suites Sikeston I-55 also features laundry facilities, a front desk safe, and a lift. Self parking is free.
  • 64 guestrooms or units
  • 3 levels
  • Business facilities
  • Self-service laundry
  • Front desk (24 hours)
  • Front desk safe
  • Lift
Comfort Inn & Suites Sikeston I-55 offers 64 air-conditioned accommodations, with coffee/tea makers. Guests can surf the web using complimentary wireless Internet access.

Bathrooms include baths or showers. Business-friendly amenities include desks and telephones.

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Best Western Plus Sikeston I-55
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  • Pool
  • Breakfast included
  • Pet-friendly
  • Parking included
4.2 out of 5, Very good, 1,012 reviews
The price is AU$141
includes taxes & fees
14 July - 15 July
Best Western Plus Sikeston I-55

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Free self parking on site
  • Limited on-site self parking
  • Wheelchair-accessible parking available

Things to do

  • Gym
  • Indoor pool

Family friendly

  • Indoor pool
  • Laundry facilities

Conveniences

  • 24-hour front desk
  • Laundry facilities
  • Safe at front desk

Business services

  • Business centre

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Lift
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible registration desk

More

  • 3 floors
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided

Bathroom

  • Bathtub or shower
  • Private bathroom
  • Towels provided

Entertainment

  • Cable/satellite channels

Food and drink

  • Coffee/tea maker

More

  • Air conditioning
  • Desk
  • Phone

Policies

Check-in

Check-in start time: 2:00 PM; check-in end time: anytime
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 20 per pet, per night
  • Only dogs and cats are allowed
  • Maximum 2 (weight limit: 20 lb per pet)
  • Certain rooms only
  • You can request a pet-friendly room by reaching out to the property at the number on the booking confirmation
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are not available.
  • Cots (infant beds) are not available.

Payment types

Important information

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Pet fee: USD 20 per pet, per night
  • Service animals are exempt from fees

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, American Express, Discover, JCB International and Carte Blanche. Cash is not accepted. This property affirms that it follows the cleaning and disinfection practices of Commitment to Clean (Choice) guidelines.

We should mention

  • Pets are welcome in specific rooms only, which can be requested by contacting the property directly at the number on your booking confirmation (please see the Fees section for related charges).

Property is also known as

Comfort Inn Sikeston Hotel
Comfort Inn Sikeston

Frequently asked questions

What is the cancellation policy at Comfort Inn & Suites Sikeston I-55?

Comfort Inn & Suites Sikeston I-55 offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at Comfort Inn & Suites Sikeston I-55?

As of 15 June 2026, prices found for a 1-night stay for 2 adults at Comfort Inn & Suites Sikeston I-55 on 6 July 2026 start from AU$157, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at Comfort Inn & Suites Sikeston I-55?

Yep, Comfort Inn & Suites Sikeston I-55 has a free self car park.

Does Comfort Inn & Suites Sikeston I-55 have a pool?

Comfort Inn & Suites Sikeston I-55 has an indoor pool.

Is there a free airport shuttle available at Comfort Inn & Suites Sikeston I-55?

No, Comfort Inn & Suites Sikeston I-55 does not offer an airport shuttle service.

What time are check-in & check-out at Comfort Inn & Suites Sikeston I-55?

Check-in begins at 2:00 PM. Check-out time is 11:00 AM.

Comfort Inn & Suites Sikeston I-55 Reviews

Reviews

8.4

Very good

Rating 10 - Excellent. 141 out of 295 reviews
Rating 8 - Good. 94 out of 295 reviews
Rating 6 - Okay. 30 out of 295 reviews
Rating 4 - Poor. 19 out of 295 reviews
Rating 2 - Terrible. 11 out of 295 reviews

8.4/10

Cleanliness

8.8/10

Staff & service

8.2/10

Amenities

8.2/10

Property conditions & facilities

Reviews

Verified

10/10 Excellent

aileen

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel was very clean, beds were comfortable, and staff was friendly and helpful.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Dorothy

facility was very clean. night staff was a pleasure and most helpful. very nice room with lots of space. great stay! good breakfast as well.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Soo

Liked: Cleanliness, staff & service, amenities
Very nice staff & clean room
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Connie

Liked: Cleanliness, property conditions & facilities
Room was clean, breakfast was very good.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

JESSICA

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It was a very nice stay. The pool was clean and enjoying!
Stayed 1 night in Jul 2025
Verified

10/10 Excellent

Jamaal

Liked: Cleanliness, staff & service, amenities
Awesome no complaints
Stayed 2 nights in Nov 2025
Verified

10/10 Excellent

jacqueline

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
It was quiet and peaceful. It was by everything we wanted to go.
Stayed 2 nights in Oct 2025
Verified

8/10 Good

Amanda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice hotel with great staff. Room was fine, breakfast could be better but overall a good stay for this area.
Verified

10/10 Excellent

Sasha

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We were happy with our stay
Stayed 1 night in Oct 2024
Verified

10/10 Excellent

Shonta'

Liked: Cleanliness, staff & service, property conditions & facilities
Love Everything
Stayed 4 nights in Oct 2025
Verified

10/10 Excellent

Kimberly

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We were in town for a pit-stop to sleep and the staff was very nice. Comfy beds and nice location
Stayed 1 night in Mar 2025
Verified

10/10 Excellent

Shonta'

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The Jacuzzi was the Best!!! 👏
Stayed 6 nights in Oct 2025
Verified

8/10 Good

Walter

Liked: Cleanliness, staff & service, property conditions & facilities
Good place to spend a night
Stayed 1 night in Mar 2025
Verified

10/10 Excellent

Tammi

Liked: Cleanliness, staff & service, property conditions & facilities
Very clean, nice staff and good breakfast
Stayed 1 night in Aug 2023
Verified

10/10 Excellent

Peggy

Liked: Cleanliness, staff & service, property conditions & facilities
The facility was very nice.
Stayed 2 nights in May 2025
Verified

8/10 Good

Denise

hotel was fine clean and convient
Stayed 1 night in Feb 2025
Verified

10/10 Excellent

John

Liked: Cleanliness, staff & service, property conditions & facilities
Great for overnights, staff friendly and attentive
Stayed 1 night in Apr 2024
Verified

10/10 Excellent

Cindy

Place was great
Stayed 1 night in May 2024
Verified

10/10 Excellent

Mike

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Clean, and available rooms when we needed it most due to storms
Stayed 1 night in Feb 2025
Verified

8/10 Good

Dylan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Right off the main drag, huge complimentary breakfast area
Stayed 1 night in May 2024
Verified

8/10 Good

John

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Good stay

It was decent…slept well The room was clean
Stayed 1 night in May 2025
Verified

10/10 Excellent

Michael

Liked: Cleanliness, staff & service, property conditions & facilities
Conveniant to I55, clean, and comfortable,
Stayed 1 night in Dec 2024
Verified

10/10 Excellent

Jacqueline

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

A great place to stay!

Always a friendly and helpful staff. Great breakfast in the mornings.
Stayed 1 night in Jul 2022
Verified

8/10 Good

Alan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The room was chilly. Didn't seem to warm up to our satisfaction.
Stayed 1 night in Nov 2025