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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Hotel in Cape Girardeau with full-service spa and free breakfast

Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Exterior
Free breakfast
Indoor pool, open 8 AM to 11 PM, pool loungers
Premium bedding, down duvets, pillow-top beds, in-room safe
Exterior

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Laundry
  • Housekeeping
The current price is AU$171
includes taxes & fees
30 Nov - 1 Dec

Explore the area

View map
3253 William Street, Cape Girardeau, MO, 63701
  • Place, Saint Francis Medical Center
    ‪6 min walk‬
  • Place, Southeast Missouri State University
    ‪6 min drive‬
  • Place, Isle Casino Cape Girardeau
    ‪8 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪5 min drive‬

Room options

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
  • 37 sq m
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.6 out of 10
Exceptional
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed

9.6 out of 10
Exceptional
(32 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 2 Queen Beds

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(52 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(14 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
  • 37 sq m
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 Queen Bed

Premium bedding, down duvets, pillow-top beds, in-room safe

Standard Room, 1 Queen Bed

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Pillow-top bed
Down duvet
  • 37 sq m
  • Sleeps 2
  • 1 Queen Bed

View all photos for Standard Room

Premium bedding, down duvets, pillow-top beds, in-room safe

Standard Room

8.4 out of 10
Very good
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
  • 37 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 Bedroom (Feature)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Pillow-top bed
Down duvet
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 1 King Bed, Accessible (Mobility)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
  • Sleeps 2
  • 1 King Bed

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About the area

Cape Girardeau

At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG you'll be within a 15-minute walk of Saint Francis Medical Center and 4 km (2.5 mi) from Saint Francis Healthcare System. Highlights at this hotel include a full-service spa, an indoor swimming pool and free breakfast. .Enjoy the gym and pool loungers. 118 square feet (11 square metres) of event facilities include a meeting room and conference space, and other business amenities include a business centre. Other amenities include free Wi-Fi in public areas and laundry facilities. There's also the convenience of free self parking. .Attractions within a 10-minute drive of this Cape Girardeau hotel include Shawnee National Forest and Mississippi River.

What's nearby

  • Saint Francis Medical Center - 6 min walk - 0.6 km
  • Southeast Missouri Hospital - 5 min drive - 5.3 km
  • Southeast Missouri State University - 6 min drive - 6.3 km
  • Isle Casino Cape Girardeau - 8 min drive - 9.1 km
  • Show Me Center - 9 min drive - 9.1 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬7 min walk
  • ‪Rhodes - ‬20 min walk
  • ‪White Castle - ‬10 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪Chili's Grill & Bar - ‬4 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel in Cape Girardeau with full-service spa and free breakfast
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers its guests a full-service spa, an indoor pool, and a fitness centre. Public spaces have free WiFi and wired Internet. A business centre and a meeting room are available. Free breakfast is served. Event space at this hotel measures 118 square feet (11 square metres) and includes conference space. The business-friendly Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG also features a vending machine, complimentary newspapers in the lobby, and laundry facilities. Self parking is free.

This Cape Girardeau hotel is smoke free.

  • 1 building
  • 102 guestrooms or units
  • 4 levels
  • 118 sq ft of conference space
  • 11 sq. m of conference space
  • Breakfast available (free)
  • Poolside lounge chairs
  • Business facilities
  • Conference space
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Storage area for luggage
  • Front desk safe
  • Newspapers in lobby (free)
  • Bellhop
  • No smoking on site
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers 102 accommodations with a safe and coffee/tea makers. This accommodation offers separate sitting areas. Pillowtop beds feature down duvets and premium bedding. A pillow menu is available. 52-inch flat-screen televisions come with premium cable channels. Bathrooms include complimentary toiletries and hairdryers.

Guests can surf the web using complimentary wired and wireless Internet access. Business-friendly amenities include desks and telephones; free local calls are provided (restrictions may apply). Housekeeping is provided on a daily basis.

Guests can indulge in a pampering treatment at the hotel's full-service spa.

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includes taxes & fees
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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transport

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop

Business services

  • 118 square feet of conference space
  • Business centre
  • Meeting room

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Smoke-free property

Room amenities

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; check-in end time: anytime
Contactless check-in and check-out are available
Minimum check-in age - 21

Check-out

Check-out before 11 AM
Contactless check-out

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • No pets allowed

Children and extra beds

  • Children are welcome.
  • Cots (infant beds) are not available.

Payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International and Carte Blanche. Cash is not accepted. For guests' safety, the property includes a smoke detector in all accommodation. Cashless payment methods are available for all transactions. This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG) guidelines.

We should mention

  • Pool access available from 8 AM to 11 PM
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

What is the cancellation policy at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of 11 Nov 2025, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on 30 Nov 2025 start from AU$170.91, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yep, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG has a free self car park.

Is there a spa on site at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yep, there is an onsite spa at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG has a pool and an indoor pool. Grab your bathers and lounge poolside while enjoying on a lounger. The pool is open 8 AM to 11 PM.

Is there a free airport shuttle available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG does not offer an airport shuttle service.

What time are check-in & check-out at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-in begins at 3:00 PM. Check-out time is 11 AM.

Are pets allowed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, pets are not allowed.