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21c Museum Hotel Louisville

4.5 star property
Luxury hotel with full-service spa, steps from Louisville Slugger Museum

Photo gallery for 21c Museum Hotel Louisville

Room (Asleep in the Cyclone)
Interior
Breakfast, lunch and dinner served
Fountain
Room (Asleep in the Cyclone)

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Spa
  • Pet-friendly
  • Free Wi-Fi
  • Air-conditioning
  • Gym
The current price is AU$305
includes taxes & fees
17 Feb - 18 Feb

Explore the area

View map
700 W Main Street, Louisville, KY, 40202
  • Place, 21c Museum Hotel
    ‪1 min walk‬
  • Place, Louisville Slugger Museum
    ‪3 min walk‬
  • Place, KFC Yum Center
    ‪8 min walk‬
  • Airport, Louisville, KY (SDF-Louisville Intl.)
    ‪10 min drive‬

Room options

View all photos for Deluxe Double Room, 2 Double Beds

Deluxe Double Room, 2 Double Beds

Deluxe Double Room, 2 Double Beds

9.6 out of 10
Exceptional
(31 reviews)
  • 31 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Luxury Double Room, 2 Double Beds

Luxury Double Room, 2 Double Beds

Luxury Double Room, 2 Double Beds

9.0 out of 10
Wonderful
(2 reviews)
  • City view
  • 40 sq m
  • 1 bedroom
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed

9.6 out of 10
Exceptional
(68 reviews)
  • 33 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Luxury Room, 1 King Bed

Luxury Room, 1 King Bed

Luxury Room, 1 King Bed

9.0 out of 10
Wonderful
(34 reviews)
  • City view
  • 42 sq m
  • 1 bedroom
  • Sleeps 3
  • 1 King Bed

View all photos for Suite, Corner

Suite, Corner

Suite, Corner

  • City view
  • 61 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Room (Asleep in the Cyclone)

Room (Asleep in the Cyclone)

Room (Asleep in the Cyclone)

  • 46 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Suite (Atrium)

Suite (Atrium)

Suite (Atrium)

  • 54 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Room, Balcony

Room, Balcony

Room, Balcony

10.0 out of 10
Exceptional
(1 review)
  • City view
  • 29 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Double Room, Accessible

Designer toiletries, hair dryer, bathrobes, towels

Deluxe Double Room, Accessible

9.0 out of 10
Wonderful
(2 reviews)
  • 42 sq m
  • Sleeps 4
  • 2 Double Beds

View all photos for Deluxe Room, 1 King Bed, Accessible

Premium bedding, down duvets, minibar, in-room safe

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(1 review)
  • 40 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed, Accessible

Premium bedding, down duvets, minibar, in-room safe

Deluxe Room, 1 King Bed, Accessible

10.0 out of 10
Exceptional
(1 review)
  • 40 sq m
  • Sleeps 3
  • 1 King Bed

View all photos for Apartment, 1 Double Bed (Rooftop)

Apartment, 1 Double Bed (Rooftop)

Apartment, 1 Double Bed (Rooftop)

  • City view
  • Sleeps 4
  • 1 Double Bed

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About the area

Louisville

A luxury stay in the heart of Louisville awaits you at 21c Museum Hotel Louisville. Within steps you'll find Louisville Slugger Museum and KFC Yum Center within a 10-minute stroll. Highlights at this boutique hotel include in-room free WiFi, free high-speed Internet and LCD TVs. .A day of pampering at 21c Spa can include deep-tissue massages and hot stone massages along with access to the sauna and steam room. The fine-dining restaurant, Proof on Main, is open for breakfast, brunch, lunch and dinner. The hotel's own lounge bar is a nice place to enjoy a drink. 5000 square feet (465 square metres) of event facilities include meeting rooms and conference space, and other business amenities include a 24-hour business centre and limo/town car service. Plus you'll find free Wi-Fi in public areas, a 24-hour gym and coffee/tea in a common area. Full breakfast is available on weekdays between 7:00 AM and 10:00 AM and on weekends between 8:00 AM and 1:00 PM. Bring your pet along and take advantage of this property's pet-friendly amenities, such as food and water bowls. There's also the convenience of valet parking. .Attractions within a 15-minute walk of this 4.5-property class Downtown Louisville hotel include Kentucky International Convention Center and Whiskey Row.

What's nearby

  • 21c Museum Hotel - 1 min walk - 0.0 km
  • Muhammad Ali Center - 3 min walk - 0.3 km
  • Louisville Slugger Museum - 3 min walk - 0.3 km
  • Kentucky International Convention Center - 8 min walk - 0.7 km
  • KFC Yum Center - 8 min walk - 0.7 km

Getting around

  • Louisville International Airport (SDF) - 10 min drive

Restaurants

  • ‪Jockey Silks Bourbon Bar - ‬7 min walk
  • ‪Heine Brothers' Coffee - ‬3 min walk
  • ‪Vincenzo's Italian Restaurant - ‬5 min walk
  • ‪Swizzle - ‬8 min walk
  • ‪Sunergos Coffee and Espresso Bar - ‬6 min walk

About this property

21c Museum Hotel Louisville

Luxury hotel with full-service spa, steps from Louisville Slugger Museum
21c Museum Hotel Louisville offers its guests a full-service spa and a 24-hour fitness centre. There's a restaurant on site. You can enjoy a drink at the bar/lounge. A computer station is on site, and both WiFi and wired Internet are free in public spaces.

A 24-hour business centre, meeting rooms, and limo/town car service are available. Event space at this hotel measures 5000 square feet (465 square metres) and includes conference space. Spa services, multilingual staff, and gift shops/newsstands are also featured at the luxury 21c Museum Hotel Louisville. Parking is available for a fee.

This 4.5-star Louisville hotel is smoke free.

  • 1 building
  • 91 guestrooms or units
  • 4 levels
  • Conference rooms
  • 5000 sq ft of conference space
  • 465 sq. m of conference space
  • Built in 2006
  • Charging station for electric cars
  • Business centre (24 hours)
  • Conference space
  • Breakfast available (surcharge)
  • Coffee in lobby
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Staff members are multilingual
  • Storage area for luggage
  • Front desk safe
  • Car service
  • Tour and ticket information
  • Concierge
  • Gift shop
  • ATM
  • Bellhop
  • Lift
  • No smoking on site
  • Bar or lounge
  • Dining venue
21c Museum Hotel Louisville offers 91 accommodations with minibars and laptop-compatible safes. Beds feature down duvets and premium bedding. 50-inch LCD televisions come with premium cable channels. Bathrooms include bathrobes, designer toiletries, complimentary toiletries and hairdryers.

This Louisville hotel provides complimentary wired and wireless Internet access. Business-friendly amenities include desks along with free local calls (restrictions may apply). Additionally, rooms include espresso makers and complimentary bottles of water. In-room massages and hypo-allergenic bedding can be requested. Housekeeping is provided on a daily basis.

21c Spa has 2 treatment rooms. Services include deep-tissue massages, hot stone massages, sports massages and Swedish massages. The spa is equipped with a sauna and a steam room. The spa is open daily.

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Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transport

  • Electric car charging station on site
  • Limo/town car service
  • Valet parking on site (USD 32 per night; includes in/out privileges)
  • Limited on-site valet parking
  • Wheelchair-accessible parking available

Food and drink

  • Full breakfast available for a fee 7:00 AM to 10:00 AM on weekdays and 8:00 AM to 1:00 PM on weekends; USD 5 to 25 per person
  • A bar/lounge
  • A restaurant
  • Coffee and tea in common areas

Restaurants on site

  • Proof on Main

Things to do

  • 24-hour gym
  • Full-service spa
  • Yoga classes

Family friendly

  • In-room cot
  • Laundry facilities
  • Rollaway/extra bed (surcharge)
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Gift shop/newsstand
  • Laundry facilities
  • Luggage storage
  • Safe at front desk

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Multilingual staff
  • Porter/bellhop
  • Tour and ticket assistance

Business services

  • 24-hour business centre
  • 5,000 square feet of conference space
  • Computer station
  • Meeting rooms

Full-service spa

  • 2 treatment rooms
  • Deep-tissue massages
  • Hot stone massages
  • In-room massages
  • Prenatal massages
  • Sauna
  • Spa open daily
  • Sports massages
  • Steam room
  • Swedish massages

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Lift
  • Wheelchair accessibility
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible registration desk

More

  • 1 building
  • 4 floors
  • At least 80% lighting from LEDs
  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • Built in 2006
  • Comprehensive food waste policy
  • Double-glazed windows
  • Eco-friendly cleaning products used
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property
  • Vegan dining options

Room amenities

Bedroom

  • Blackout drapes
  • Down comforter
  • Free cot
  • Hypo-allergenic bedding
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Designer toiletries
  • Dressing gowns
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • 50-inch LCD TV with premium cable channels
  • IPod dock

Food and drink

  • Champagne service
  • Espresso maker
  • Free bottled water
  • Limited room service
  • Minibar

More

  • Air conditioning (climate-controlled)
  • Cleaning products are eco-friendly
  • Connecting rooms available
  • Desk
  • Eco-friendly toiletries
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Laptop-compatible safe
  • LED lighting
  • Soundproofed rooms
  • Water-efficient showers

Policies

Check-in

Check-in start time: 4 PM; check-in end time: midnight
Contactless check-in and check-out are available
Minimum check-in age - 21

Check-out

Check-out before 11 AM
Contactless check-out

Special check-in instructions

Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

  • Pets: USD 40.00 per accommodation, per stay
  • Weight limit: 50 lb per pet
  • Food and water bowls are available
    • Service animals are exempt from fees.

Children and extra beds

  • Children are welcome.
  • Rollaway/extra beds are available for USD 30.0 per night.
  • Free cots (infant beds)!

Payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Service fee: USD 5.00 per accommodation, per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for full breakfast: approximately USD 5 to 25 per person
  • Valet parking fee: USD 32 per night (in/out privileges)
  • Pet fee: USD 40.00 per accommodation, per stay
  • Service animals are exempt from fees
  • Rollaway bed fee: USD 30.0 per night

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
This property uses eco-friendly cleaning products
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit and window guards
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels)
Charges for extra guests may apply and vary according to property policy.
A credit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guest room reservation. This property accepts Visa, Mastercard, American Express and Discover. Cash is not accepted. This property uses eco-friendly cleaning products.
    For guests' safety, the property includes a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit and window guards in all accommodation. This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels) guidelines.

We should mention

  • Reservations are needed for massage services. For reservations, contact the hotel before arrival using the contact information on the booking confirmation.
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

21c Hotel Louisville
21c Hotel Museum
21c Louisville Hotel
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21c Museum Hotel
21c Museum Hotel Louisville
21c Museum Louisville
Louisville 21c Hotel
Louisville 21c Museum
Museum Hotel 21c
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Frequently asked questions

What is the cancellation policy at 21c Museum Hotel Louisville?

21c Museum Hotel Louisville offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at 21c Museum Hotel Louisville?

As of 16 Feb 2026, prices found for a 1-night stay for 2 adults at 21c Museum Hotel Louisville on 17 Feb 2026 start from AU$297.75, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at 21c Museum Hotel Louisville?

Yep, 21c Museum Hotel Louisville has valet parking with in/out privileges for USD 32 per night.

Is there a spa on site at 21c Museum Hotel Louisville?

Yep, 21c Spa is available for guests. It has a steam room and a sauna. You'll enjoy services like prenatal massages.

What makes 21c Museum Hotel Louisville a romantic place to stay?

A champagne service and a lounge bar, as well as premium bedding and massage services available in the guestrooms, help set the scene for a romantic weekend at 21c Museum Hotel Louisville.

Is 21c Museum Hotel Louisville family-friendly?

You bet! With amenities such as laundry facilities, as well as free infant beds in the guestrooms, it's no surprise that 21c Museum Hotel Louisville is a hit with families.

Does 21c Museum Hotel Louisville serve breakfast?

You bet, full brekkie is on offer weekdays between 7:00 AM and 10:00 AM and on weekends from 8:00 AM to 1:00 PM.

Is there a free airport shuttle available at 21c Museum Hotel Louisville?

No, 21c Museum Hotel Louisville does not offer an airport shuttle service.

Is there a bar or restaurant at 21c Museum Hotel Louisville?

Yep, they've got a lounge bar and an onsite restaurant that serves breakfast, brunch, lunch and dinner.

What time are check-in & check-out at 21c Museum Hotel Louisville?

Check-in begins at 4 PM. Check-out time is 11 AM.

Are pets allowed at 21c Museum Hotel Louisville?

Furry friends are welcome at 21c Museum Hotel Louisville, with food and water bowls on offer. Just so you know, there's a weight limit of up to 23 kg per pet.

21c Museum Hotel Louisville Reviews

Reviews

9.4

Exceptional

Rating 10 - Excellent. 770 out of 1006 reviews
Rating 8 - Good. 134 out of 1006 reviews
Rating 6 - Okay. 62 out of 1006 reviews
Rating 4 - Poor. 22 out of 1006 reviews
Rating 2 - Terrible. 18 out of 1006 reviews

9.6/10

Cleanliness

9.4/10

Staff & service

9.0/10

Amenities

9.6/10

Property conditions & facilities

Reviews

10/10 Excellent

Clark and Margaret

Travelled with family
Liked: Cleanliness, amenities, property conditions & facilities
Room clean , comfortable and quiet.
Stayed 1 night in Nov 2025

10/10 Excellent

Keith

Stayed 1 night in Nov 2025

6/10 Okay

Dwight

Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
The room was nice and our balcony great but we paid an upgrade fee for the balcony and got an early morning (Sunday) stampede of door slamming from housekeeping who’s entrance was DIRECTLY across from our room (unbeknownst to us). Then, at 9AM, they’re knocking on our door to cleaning when checkout was at 11am. 👎😡 Whatt!? I complained to front desk at checkout but was told there was nothing they could do. I’ve stayed at many 5 star hotels around the world and this was NOT 5 star service or thinking. Ruined our stay.
Stayed 1 night in Nov 2025

10/10 Excellent

Jan Elliott

Travelled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent in every way. The art museum was an added bonus!!!
Stayed 3 nights in Nov 2025

10/10 Excellent

Glenn

Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Room comfortable and clean. Staff very helpful and friendly. Loved the art!
Stayed 1 night in Nov 2025

10/10 Excellent

david

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Beautiful environment Helpful friendly staff
Stayed 1 night in Nov 2025

8/10 Good

ABBEY

Travelled with family
Liked: Cleanliness
Bed was comfortable, room was large, bathroom was OK. Staff was kind. Wish the breakfast opened earlier on Sunday.
Stayed 3 nights in Oct 2025

10/10 Excellent

Matthew

Stayed 2 nights in Oct 2025

10/10 Excellent

John

Business traveller
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Oct 2025

10/10 Excellent

Robin, Safety Harbor

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
21c Museum Hotel is a fun and unique experience. Beautiful rooms and centrally located to shops, restaurants and distilleries in Louisville.
Stayed 2 nights in Oct 2025

8/10 Good

Richard

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast had a good variety but in some cases a little over cooked. Right on whiskey row, plenty of dining options
Stayed 3 nights in Oct 2025

10/10 Excellent

Steven

Stayed 2 nights in Oct 2025

10/10 Excellent

Erica

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved our stay, would definitely plan to come back if we are ever in the area again.
Stayed 1 night in Oct 2025

10/10 Excellent

Melissa

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We've wanted to stay at a 21c Museum hotel. We love the concept. And the room was large and well appointed. Staff was A+. We highly recommend when visiting Louisville.
Stayed 1 night in Oct 2025

8/10 Good

Thomas

Travelled with partner
Liked: Cleanliness, amenities, property conditions & facilities
Front desk and valets were great. But our room wasn't serviced, which makes the stay less comfortable.
Stayed 2 nights in Oct 2025

10/10 Excellent

Savannah

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 2 nights in Oct 2025

10/10 Excellent

Natalie

Liked: Cleanliness, staff & service, property conditions & facilities
Stayed 3 nights in Oct 2025

10/10 Excellent

Stephanie

Travelled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the strange art. I thought the building maintained the character I was expecting by the name and the reviews. Gym was actually better than the reviews.
Stayed 2 nights in Oct 2025

10/10 Excellent

earl

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect location for walking Louisville
Stayed 4 nights in Oct 2025

8/10 Good

Pamela

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Nice art
Stayed 1 night in Oct 2025

6/10 Okay

Kevin

Stayed 3 nights in Oct 2025

10/10 Excellent

Shelley

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
We only stayed 1 night, but everything was excellent
Stayed 1 night in Oct 2025

10/10 Excellent

Courtney

Liked: Cleanliness
Stayed 1 night in Sep 2025

8/10 Good

mirtha

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Good location
Stayed 2 nights in Oct 2025

10/10 Excellent

Ralph

Stayed 1 night in Sep 2025