See all properties
Save

Hilton Jacksonville At Mayo Clinic

4.5 star property
Luxury hotel with free local area shuttle and fitness centre

Photo gallery for Hilton Jacksonville At Mayo Clinic

Breakfast, lunch, dinner served; American cuisine
Meeting facility
Lobby
Exterior
Premium bedding, in-room safe, blackout curtains, iron/ironing board

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Breakfast available
  • Room service
  • 24/7 front desk
  • Bar
  • Pool
  • Housekeeping
The current price is AU$212
includes taxes & fees
23 Nov - 24 Nov

Explore the area

View map
4745 Transformation Way, Jacksonville, FL, 32224
  • Place, Mayo Clinic Florida
    ‪1 min walk‬
  • Place, St. Johns Town Center
    ‪7 min drive‬
  • Place, Mayport Naval Station
    ‪17 min drive‬
  • Airport, Jacksonville, FL (JAX-Jacksonville Intl.)
    ‪33 min drive‬

Room options

View all photos for Room, 1 King Bed

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed (Water View)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Deluxe Room, 1 King Bed (Water View)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Sofa bed - single
Premium bedding
Blackout curtains
  • Water view
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Deluxe Room, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 2
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Sofa bed - single
Premium bedding
Blackout curtains
  • Sleeps 4
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed, Corner

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed, Corner

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Sofa bed - single
Premium bedding
Blackout curtains
  • Sleeps 4
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 2
  • 1 King Bed

View all photos for Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Junior Suite, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Suite, 1 King Bed, Accessible (Mobility & Hearing, Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed (Zero Count)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed (Zero Count)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed (Water View)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed (Water View)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Water view
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed (Water View, Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed (Water View, Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Water view
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Accessible (Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed, Accessible (Hearing)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed, Accessible (Roll-In Shower)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 1 King Bed, Accessible (Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 1 King Bed, Accessible (Hearing)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 2
  • 1 King Bed

View all photos for Room, 2 Queen Beds

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible (Water View, Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible (Water View, Hearing)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Water view
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible, Bathtub

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible, Bathtub

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible (Hearing)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible (Hearing)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds (Water View)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds (Water View)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Water view
  • Sleeps 4
  • 2 Queen Beds

View all photos for Room, 2 Queen Beds, Accessible, Bathtub (View)

Premium bedding, in-room safe, blackout curtains, iron/ironing board

Room, 2 Queen Beds, Accessible, Bathtub (View)

Highlights

Air conditioning
Heating
Free cots/infant beds
Mini-fridge
Smart TV
Premium bedding
Blackout curtains
Hairdryer
  • Sleeps 4
  • 2 Queen Beds

You may also like

Ad
Terrace/patio

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Golden Glades - The Woods
  • Pool
  • Breakfast included
  • Pet-friendly
  • Parking included
4.5 out of 5, Wonderful, 1,001 reviews
The price is AU$186
includes taxes & fees
23 Nov - 24 Nov
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

About the area

Jacksonville

A luxury stay in Jacksonville awaits you at Hilton Jacksonville At Mayo Clinic. You'll be 0.5 km (0.3 mi) from Mayo Clinic Florida and 10.4 km (6.5 mi) from St. Johns Town Center. Highlights at this hotel include a restaurant, an outdoor swimming pool and free self-parking. .The restaurant, Coastal Kitchen, serves American cuisine and is open for breakfast, lunch and dinner. Coastal Kitchen Bar is the hotel's own cocktail bar. Enjoy the gym and pool loungers. Other amenities include free Wi-Fi in public areas and laundry facilities. Each morning buffet breakfast is served between 6:00 AM and 10:30 AM. There's also the convenience of a free area shuttle. .Attractions within a 20-minute drive of this 4.5-property class Jacksonville hotel include University of North Florida and TPC Sawgrass.

What's nearby

  • Mayo Clinic Florida - 1 min walk - 0.0 km
  • University of North Florida - 5 min drive - 8.3 km
  • St. Johns Town Center - 7 min drive - 10.9 km
  • Mayport Naval Station - 17 min drive - 19.2 km
  • Jacksonville Naval Air Station - 29 min drive - 47.0 km

Getting around

  • Jacksonville Station - 28 min drive
  • Jacksonville International Airport (JAX) - 31 min drive

Restaurants

  • ‪Culver's #964 - ‬3 min drive
  • ‪M Brothers at Mayo - ‬14 min walk
  • ‪Starbucks - ‬3 min drive
  • ‪Circle K - ‬16 min walk
  • ‪Mayo Clinic - Employee Cafeteria - ‬14 min walk

About this property

Hilton Jacksonville At Mayo Clinic

Luxury hotel with free local area shuttle and fitness centre
Hilton Jacksonville At Mayo Clinic offers its guests an outdoor pool and a fitness centre. There's a restaurant on site. You can enjoy a drink at the bar/lounge. Public spaces have free WiFi.

Business amenities include 12 meeting rooms and coworking spaces. Event space at this hotel measures 20000 square feet (1858 square metres) and includes conference space. The luxury Hilton Jacksonville At Mayo Clinic also features concierge services, laundry facilities, and dry cleaning/laundry services. A free area shuttle within 350 yards is available. Self parking is free.

This 4.5-star Jacksonville hotel is smoke free.

  • 1 building
  • 252 guestrooms or units
  • 8 levels
  • Conference rooms
  • 20000 sq ft of conference space
  • 1858 sq. m of conference space
  • Built in 2025
  • Poolside lounge chairs
  • Umbrellas for the pool
  • Charging station for electric cars
  • Conference space
  • Breakfast available (surcharge)
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Express check-out
  • Storage area for luggage
  • Concierge
  • Wedding services available
  • Corner/local shop
  • Television in lobby
  • Bellhop
  • No smoking on site
  • Bar or lounge
  • Dining venue
Hilton Jacksonville At Mayo Clinic offers 252 air-conditioned accommodations with laptop-compatible safes and complimentary bottles of water. Beds feature premium bedding. 55-inch Smart televisions come with premium cable channels and Netflix. Bathrooms include baths or showers and hairdryers.

Guests can surf the web using the complimentary wireless Internet access (speed: 25+ Mbps). Business-friendly amenities include telephones; local and long-distance calls are complimentary (restrictions may apply). Additionally, rooms include coffee/tea makers and an iron/ironing board. Housekeeping is provided on a daily basis.

Similar properties

On the beach, white sand, surfing, kayaking
Margaritaville Jacksonville Beach
  • Pool
  • Free WiFi
  • Restaurant
  • Air conditioning
4.5 out of 5, Wonderful, 3,347 reviews
Margaritaville Jacksonville Beach

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • In-room WiFi speed: 25+ Mbps
  • Available in some public areas: Free WiFi

Parking and transport

  • Electric car charging station on site
  • Free area shuttle up to 350 yards
  • Free uncovered self parking on site

Food and drink

  • Daily buffet breakfast available 6:00 AM to 10:30 AM for a fee: USD 26.99 to 26.99 for adults and USD 15 to 21 for children
  • A bar/lounge
  • A restaurant

Restaurants on site

  • Coastal Kitchen
  • Coastal Kitchen Bar

Things to do

  • Gym
  • Outdoor pool
  • TV in common areas

Family friendly

  • Free area shuttle
  • Grocery/convenience store
  • In-room cot
  • Laundry facilities
  • Mini-fridge
  • Outdoor pool
  • Rollaway/extra bed (surcharge)

Conveniences

  • 24-hour front desk
  • Grocery/convenience store
  • Laundry facilities
  • Luggage storage

Guest services

  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop
  • Proposal/romance packages
  • Wedding services

Business services

  • 12 meeting rooms
  • 20,000 square feet of conference space
  • Coworking space

Outdoors

  • Firepit
  • Outdoor furniture
  • Pool loungers
  • Pool umbrellas

Accessibility

  • Tile flooring in public areas

More

  • 1 building
  • 8 floors
  • At least 80% lighting from LEDs
  • At least 80% of food locally-sourced
  • Built in 2025
  • Comprehensive food waste policy
  • Smoke-free property
  • Traditional architecture
  • Vegetarian breakfast available
  • Vegetarian dining options

Room amenities

Bedroom

  • Blackout drapes
  • Free cot
  • Premium bedding
  • Rollaway/extra bed (surcharge)

Bathroom

  • Bathtub or shower
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 55-inch smart TV with premium cable channels
  • Netflix
  • Streaming services

Food and drink

  • Coffee/tea maker
  • Free bottled water
  • Late-night room service
  • Mini-fridge

More

  • Air conditioning
  • Free local calls
  • Free long-distance calls
  • Heating
  • Iron/ironing board
  • Laptop-compatible safe
  • LED lighting
  • Mobile key entry
  • Phone
  • Recycling
  • Water-efficient showers
  • Water-efficient toilets

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 5:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM
Contactless check-out
Express check-out available

Special check-in instructions

Front desk staff will greet guests on arrival at the property
If you are planning to arrive after 11:00 PM please contact the property in advance using the information on the booking confirmation
The credit card used to book the reservation must be presented by the cardholder at check-in along with matching photo identification, and other arrangements must be coordinated with the property prior to arrival

Access methods

Staffed front desk

Pets

  • No pets allowed

Children and extra beds

  • Children are welcome.
  • Kids stay free! Up to 2 children aged 18 years old and younger stay free per registered adult when using existing bedding.
  • Rollaway/extra beds are available for USD 50.00 per night.
  • Free cots (infant beds)!

Payment types

Important information

Fees

Guests will be asked to pay the following charges at the property:

  • Breakage deposit: USD 100 per stay

We've listed all charges provided to us by the property.

Optional extras

The fees and deposits listed below will be charged at the time of service, check-in, or check-out.

  • Fee for buffet breakfast: approximately USD 26.99 to 26.99 for adults and USD 15 to 21 for children
  • Rollaway bed fee: USD 50.00 per night

This may not be a comprehensive list. Fees and deposits are subject to change and might not include tax.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards and debit cards; cash is not accepted
This property reserves the right to pre-authorise the guest's credit card prior to arrival.
Cashless transactions are available
Safety features at this property include a carbon monoxide detector and a smoke detector
Charges for extra guests may apply and vary according to property policy.
A credit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. The name on the credit card used at check-in to pay for incidentals must be the primary name on the guest room reservation. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, Carte Blanche and debit cards. Cash is not accepted. This property reserves the right to pre-authorise the guest's credit card prior to arrival.
    For guests' safety, the property includes a carbon monoxide detector and a smoke detector in all accommodation. Cashless payment methods are available for all transactions and guests can access their rooms with a mobile device.

We should mention

  • Pool access available from 8:00 AM to 10:00 PM
  • Up to 2 children aged 18 years old and younger stay free per registered adult in the same room as the parent or guardian when using existing bedding.
  • Registered guests are the only ones allowed to be in guestrooms.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Hilton Jacksonville At Mayo Clinic Hotel
Hilton Jacksonville At Mayo Clinic Jacksonville
Hilton Jacksonville At Mayo Clinic Hotel Jacksonville

Frequently asked questions

Is parking available at Hilton Jacksonville At Mayo Clinic?

Yep, Hilton Jacksonville At Mayo Clinic has a free self car park.

How much does it cost to stay at Hilton Jacksonville At Mayo Clinic?

As of 14 Nov 2025, prices found for a 1-night stay for 2 adults at Hilton Jacksonville At Mayo Clinic on 23 Nov 2025 start from AU$212.46, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Are there any beaches close to Hilton Jacksonville At Mayo Clinic?

The closest beach to Hilton Jacksonville At Mayo Clinic is Northeast Florida Beaches (6.3 km).

Does Hilton Jacksonville At Mayo Clinic have a pool?

Hilton Jacksonville At Mayo Clinic has an outdoor pool. Grab your bathers and lounge poolside while enjoying under the shade of an umbrella. The pool is open 8:00 AM to 10:00 PM.

What makes Hilton Jacksonville At Mayo Clinic a romantic place to stay?

Romance packages and a lounge bar, as well as premium bedding in the guestrooms, all help set the scene for a romantic weekend at Hilton Jacksonville At Mayo Clinic.

Is Hilton Jacksonville At Mayo Clinic family-friendly?

You bet! With amenities such as children's meals and a corner/local shop, as well as free infant beds in the guestrooms, it's no surprise that Hilton Jacksonville At Mayo Clinic is a hit with families.

Does Hilton Jacksonville At Mayo Clinic serve breakfast?

Sure does, buffet breakfast is offered daily from 6:00 AM to 10:30 AM.

Is there a free airport shuttle available at Hilton Jacksonville At Mayo Clinic?

No, Hilton Jacksonville At Mayo Clinic does not offer an airport shuttle service.

Is there a bar or restaurant at Hilton Jacksonville At Mayo Clinic?

Yep, they've got a lounge bar and an onsite restaurant that serves American cuisine. Pre dinner cocktails anyone?

What time are check-in & check-out at Hilton Jacksonville At Mayo Clinic?

Check-in begins at 4:00 PM. Check-out time is 11:00 AM.

Are pets allowed at Hilton Jacksonville At Mayo Clinic?

No, pets are not allowed.