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Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Hotel in Cape Girardeau with full-service spa and free breakfast

Photo gallery for Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Exterior
Free breakfast
Premium bedding, down duvets, pillow-top beds, in-room safe
Indoor pool, open 8 AM to 11 PM, pool loungers
Exterior

Reviews

9.4 out of 10
Exceptional

Popular amenities

  • Laundry
  • Housekeeping
The current price is AU$172
includes taxes & fees
16 Nov - 17 Nov

Explore the area

View map
3253 William Street, Cape Girardeau, MO, 63701
  • Place, Saint Francis Medical Center
    ‪6 min walk‬
  • Place, Southeast Missouri State University
    ‪6 min drive‬
  • Place, Isle Casino Cape Girardeau
    ‪8 min drive‬
  • Airport, Cape Girardeau, MO (CGI-Cape Girardeau Municipal)
    ‪5 min drive‬

Room options

View all photos for Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

Suite, 2 Queen Beds, Accessible (Roll-In Shower)

8.0 out of 10
Very good
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
Separate sitting area
Air-conditioning
Connecting/adjoining rooms available
Pillow menu
Down comforter
Pillowtop mattress
  • 37 sq m
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 1 King Bed, Accessible (Roll-In Shower)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed, Accessible (Roll-In Shower)

9.6 out of 10
Exceptional
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
Separate sitting area
Air-conditioning
Connecting/adjoining rooms available
Pillow menu
Down comforter
Pillowtop mattress
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed

9.6 out of 10
Exceptional
(32 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
Separate sitting area
Air-conditioning
Connecting/adjoining rooms available
Pillow menu
Down comforter
Pillowtop mattress
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 2 Queen Beds

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 2 Queen Beds

9.6 out of 10
Exceptional
(52 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
Separate sitting area
Air-conditioning
Connecting/adjoining rooms available
Pillow menu
Down comforter
Pillowtop mattress
  • Sleeps 6
  • 2 Queen Beds

View all photos for Suite, 2 Queen Beds, Accessible (Mobility)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 2 Queen Beds, Accessible (Mobility)

9.4 out of 10
Exceptional
(14 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
Separate sitting area
Air-conditioning
Connecting/adjoining rooms available
Pillow menu
Down comforter
Pillowtop mattress
  • 37 sq m
  • Sleeps 6
  • 2 Queen Beds

View all photos for Standard Room, 1 Queen Bed

Premium bedding, down duvets, pillow-top beds, in-room safe

Standard Room, 1 Queen Bed

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Pillow-top bed
Down duvet
Separate sitting area
Air-conditioning
Connecting/adjoining rooms available
Pillow menu
Down comforter
Pillowtop mattress
  • 37 sq m
  • Sleeps 2
  • 1 Queen Bed

View all photos for Standard Room

Premium bedding, down duvets, pillow-top beds, in-room safe

Standard Room

8.4 out of 10
Very good
(5 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
Separate sitting area
Air-conditioning
Connecting/adjoining rooms available
Pillow menu
Down comforter
Pillowtop mattress
  • 37 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 Bedroom (Feature)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 Bedroom (Feature)

10.0 out of 10
Exceptional
(1 review)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Pillow-top bed
Down duvet
Separate sitting area
Air-conditioning
Connecting/adjoining rooms available
Pillow menu
Down comforter
Pillowtop mattress
  • Sleeps 2
  • 1 Queen Bed

View all photos for Suite, 1 King Bed, Accessible (Mobility)

Premium bedding, down duvets, pillow-top beds, in-room safe

Suite, 1 King Bed, Accessible (Mobility)

10.0 out of 10
Exceptional
(2 reviews)

Highlights

Separate sitting area
Air conditioning
Connecting rooms available
Mini-fridge
Flat-screen TV
Pillow menu
Premium bedding
Down duvet
Separate sitting area
Air-conditioning
Connecting/adjoining rooms available
Pillow menu
Down comforter
Pillowtop mattress
  • Sleeps 2
  • 1 King Bed

About the area

Cape Girardeau

At Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG you'll be within a 15-minute walk of Saint Francis Medical Center and 4 km (2.5 mi) from Saint Francis Healthcare System. Highlights at this hotel include a full-service spa, an indoor swimming pool and free breakfast. .Enjoy the gym and pool loungers. 118 square feet (11 square metres) of event facilities include a meeting room and conference space, and other business amenities include a business centre. Other amenities include free Wi-Fi in public areas and laundry facilities. There's also the convenience of free self parking. .Attractions within a 10-minute drive of this Cape Girardeau hotel include Shawnee National Forest and Mississippi River.

What's nearby

  • Saint Francis Medical Center - 6 min walk - 0.6 km
  • Riverfront Bridge Park - 6 min drive - 7.0 km
  • Southeast Missouri State University - 6 min drive - 6.3 km
  • Isle Casino Cape Girardeau - 8 min drive - 9.1 km
  • Show Me Center - 9 min drive - 9.1 km

Getting around

  • Cape Girardeau, MO (CGI-Cape Girardeau Municipal) - 10 min drive

Restaurants

  • ‪Chick-fil-A - ‬7 min walk
  • ‪Rhodes - ‬20 min walk
  • ‪White Castle - ‬10 min walk
  • ‪McDonald's - ‬10 min walk
  • ‪Chili's Grill & Bar - ‬4 min walk

About this property

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Hotel in Cape Girardeau with full-service spa and free breakfast
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers its guests a full-service spa, an indoor pool, and a fitness centre. Public spaces have free WiFi and wired Internet. A business centre and a meeting room are available. Free breakfast is served. Event space at this hotel measures 118 square feet (11 square metres) and includes conference space. The business-friendly Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG also features a vending machine, complimentary newspapers in the lobby, and laundry facilities. Self parking is free.

This Cape Girardeau hotel is smoke free.

  • 1 building
  • 102 guestrooms or units
  • 4 levels
  • 118 sq ft of conference space
  • 11 sq. m of conference space
  • Breakfast available (free)
  • Poolside lounge chairs
  • Business facilities
  • Conference space
  • Dry cleaning
  • Self-service laundry
  • Front desk (24 hours)
  • Storage area for luggage
  • Front desk safe
  • Newspapers in lobby (free)
  • Bellhop
  • No smoking on site
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers 102 accommodations with a safe and coffee/tea makers. This accommodation offers separate sitting areas. Pillowtop beds feature down duvets and premium bedding. A pillow menu is available. 52-inch flat-screen televisions come with premium cable channels. Bathrooms include complimentary toiletries and hairdryers.

Guests can surf the web using complimentary wired and wireless Internet access. Business-friendly amenities include desks and telephones; free local calls are provided (restrictions may apply). Housekeeping is provided on a daily basis.

Guests can indulge in a pampering treatment at the hotel's full-service spa.

Similar properties

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Drury Plaza Hotel Cape Girardeau Conference Center
  • Pool
  • Hot tub
  • Breakfast included
  • Pet-friendly
4.8 out of 5, Exceptional, 1,002 reviews
The price is AU$163
includes taxes & fees
15 Nov - 16 Nov
Drury Plaza Hotel Cape Girardeau Conference Center

Property amenities

Internet

  • Available in all rooms: Free WiFi and wired internet
  • Available in some public areas: Free WiFi and wired internet

Parking and transport

  • Free self parking on site
  • Wheelchair-accessible parking available

Food and drink

  • Free breakfast available

Things to do

  • Full-service spa
  • Gym
  • Indoor pool

Family friendly

  • In-room microwave
  • Indoor pool
  • Laundry facilities
  • Mini-fridge

Conveniences

  • 24-hour front desk
  • Free newspapers in lobby
  • Laundry facilities
  • Luggage storage
  • Safe at front desk
  • Vending machine

Guest services

  • Dry cleaning/laundry service
  • Housekeeping (daily)
  • Porter/bellhop

Business services

  • 118 square feet of conference space
  • Business centre
  • Meeting room

Outdoors

  • Pool loungers

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Assistive listening devices
  • Braille/raised signage
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible parking
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible path to lift

More

  • 1 building
  • 4 floors
  • Banquet hall
  • Smoke-free property

Room amenities

Bedroom

  • Down comforter
  • Pillow menu
  • Pillowtop mattress
  • Premium bedding

Bathroom

  • Free toiletries
  • Hair dryer
  • Private bathroom
  • Shampoo
  • Soap
  • Toilet paper
  • Towels provided

Entertainment

  • 52-inch flat-screen TV with premium cable channels

Food and drink

  • Coffee/tea maker
  • Microwave
  • Mini-fridge

More

  • Air conditioning (climate-controlled)
  • Connecting rooms available
  • Desk
  • Free local calls
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Separate sitting area

Policies

Check-in

Check-in start time: 3:00 PM; check-in end time: anytime
Contactless check-in and check-out are available
Minimum check-in age - 21

Check-out

Check-out before 11 AM
Contactless check-out

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

  • No pets allowed

Children and extra beds

  • Children are welcome.
  • Cots (infant beds) are not available.

Payment types

Important information

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Cashless transactions are available
Safety features at this property include a smoke detector
This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG)
Charges for extra guests may apply and vary according to property policy.
A cash deposit, credit card or debit card for incidental charges and government-issued photo identification may be required upon check-in.
Special requests are subject to availability at the time of check-in. Special requests can't be guaranteed and may incur additional charges.
    This property is managed by a professional host. The provision of housing is linked to their trade, business or profession. This property accepts Visa, Mastercard, American Express, Discover, Diners Club, JCB International and Carte Blanche. Cash is not accepted. For guests' safety, the property includes a smoke detector in all accommodation. Cashless payment methods are available for all transactions. This property affirms that it follows the cleaning and disinfection practices of Clean Promise (IHG) guidelines.

We should mention

  • Pool access available from 8 AM to 11 PM
  • Connecting/adjoining rooms are subject to availability and can be requested by contacting the property at the number on your booking confirmation.
  • This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly).

Property is also known as

Holiday Inn Express Cape Girardeau I-55
Holiday Inn Express Hotel Cape Girardeau I-55
Holiday Inn Hotel I-55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Inn Express Cape Girarau I55
Holiday Inn Express Hotel Suites Cape Girardeau I 55
Holiday Inn Express Hotel Suites Cape Girardeau I 55 by IHG

Frequently asked questions

What is the cancellation policy at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG offers free cancellation on select room rates. Check out the cancellation policy for more info.

How much does it cost to stay at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

As of 8 Nov 2025, prices found for a 1-night stay for 2 adults at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG on 16 Nov 2025 start from AU$172.01, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is parking available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yep, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG has a free self car park.

Is there a spa on site at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Yep, there is an onsite spa at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG.

Does Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG have a pool?

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG has a pool and an indoor pool. Grab your bathers and lounge poolside while enjoying on a lounger. The pool is open 8 AM to 11 PM.

Is there a free airport shuttle available at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG does not offer an airport shuttle service.

What time are check-in & check-out at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

Check-in begins at 3:00 PM. Check-out time is 11 AM.

Are pets allowed at Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG?

No, pets are not allowed.

Reviews

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG Reviews

9.4

Exceptional

9.6/10

Cleanliness

9.6/10

Staff & service

9.2/10

Amenities

9.6/10

Property conditions & facilities

9.4/10

Eco-friendliness
Rating 10 - Excellent. 781 out of 1003 reviews
Rating 8 - Good. 151 out of 1003 reviews
Rating 6 - Okay. 39 out of 1003 reviews
Rating 4 - Poor. 16 out of 1003 reviews
Rating 2 - Terrible. 16 out of 1003 reviews

Reviews

10/10 Excellent

Jessica

Travelled with family
Liked: Amenities
The hotel was very nice and the staff were super helpful. I would stay here again!
Stayed 1 night in Aug 2025

10/10 Excellent

Dalton

Liked: Cleanliness
Stayed 1 night in Aug 2025

10/10 Excellent

Alicia

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

Robert

Travelled with family
Liked: Amenities
Great room and breakfast
Stayed 1 night in Aug 2025

10/10 Excellent

Robert

Liked: Property conditions & facilities
Stayed 1 night in Aug 2025

10/10 Excellent

Evelyn

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

10/10 Excellent

Jill

Travelled with family, Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Rooms are very nice and spacious. Liked the welcome cookies. Breakfast buffet had lots of options!
Stayed 1 night in Aug 2025

8/10 Good

Stephanie

Stayed 1 night in Aug 2025

6/10 Okay

Erica

Travelled with family and small children
Liked: Staff & service, amenities, property conditions & facilities
We thought there was going to be a hot tub! Also found hairs around in the bathroom floor and tub
Stayed 1 night in Aug 2025

8/10 Good

Bernadette

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
staff was very friendly. room clean
Stayed 2 nights in Jul 2025

4/10 Poor

Morag

Liked: Cleanliness
Disliked: Staff & service
My first experience upon walking in the door was Katy - GM who definitely let it be known that she hated her job without saying "I hate my job". Critical, rude, and talking down to me is NOT a way to give me a great first impression. She barked commands at me and ridiculed me infront of other customers for not knowing my license plate. News flash - my state changed their plates and assigned it to me 3 weeks ago. I'm more than sure there were no other vehicles from my state in your Missouri parking lot. Being told I needed to walk outside in the 103° heat index was ridiculous. The room was 78° when we entered - horribly stuffy. I did not feel like I could call the front desk for anything after being treated so badly when I checked in. Breakfast was lukewarm - not up to temp. Just kind of blah...
Stayed 1 night in Jul 2025

8/10 Good

Shivani

Liked: Cleanliness, staff & service, property conditions & facilities
Awesome. Comfortable and clean rooms. Very convenient location.
Stayed 1 night in Jul 2025

6/10 Okay

Raymond

Travelled with family and small children
Liked: Cleanliness, staff & service
It was about average. Breakfast not as expansive as some other reviews have mentioned. Pancake maker wasn't working so kiddos were disappointed. Not many allergen friendly options. Service was good and it was clean. Not our least favorite stay, not our most favorite.
Stayed 2 nights in Jul 2025

10/10 Excellent

Kathleen

Travelled with group
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Breakfast
Stayed 2 nights in Jul 2025

10/10 Excellent

Dawn

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025

4/10 Poor

Brandy

Travelled with family
Liked: Staff & service
Disliked: Cleanliness, property conditions & facilities, room comfort

Avoid if possible

Bathroom door wouldnt close, room smelled like dirty dog's and there were blood stains on the bottom sheet.
Stayed 1 night in Jul 2025

8/10 Good

Judith

Travelled with partner
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Get a lot of hallway and noise from room above. Didn’t care for the bathroom. McLean but counter was limited. Shower stall was limited in size with stool and two shower heads.
Stayed 1 night in Jul 2025

10/10 Excellent

Crystal

Liked: Cleanliness, staff & service, property conditions & facilities
Pool is nice! Place is perfect
Stayed 1 night in Jul 2025

10/10 Excellent

Penny

Travelled with family
Liked: Cleanliness, staff & service, property conditions & facilities, room comfort

Great Stay

Clean and welcoming. Tyler at the front desk for check in was engaging and friendly. He’s a gem!!
Stayed 1 night in Jul 2025

10/10 Excellent

John

Nothing
Stayed 1 night in Jul 2025

10/10 Excellent

Doug

Stayed 1 night in Jul 2025

10/10 Excellent

Christopher

Stayed 2 nights in Jul 2025

8/10 Good

Abigail

Travelled with family
Liked: Cleanliness, staff & service, amenities, property conditions & facilities
No Complaints
Stayed 1 night in Jul 2025

10/10 Excellent

Michael

Stayed 2 nights in Jul 2025

10/10 Excellent

Brandon

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Stayed 1 night in Jul 2025