The St. Regis San Francisco offers 260 accommodations, which are accessible via exterior corridors and feature minibars and laptop-compatible safes. Pillowtop beds feature Frette Italian sheets, down duvets and premium bedding. 55-inch Smart televisions come with premium cable channels and pay-per-view films. Bathrooms include dressing gowns, slippers, designer toiletries and hairdryers.
In-room wireless Internet access (speed: 25+ Mbps) is available for a surcharge. Business-friendly amenities include desks and telephones. Additionally, rooms include complimentary bottles of water and an iron/ironing board. A nightly turndown service is provided and housekeeping is offered on a daily basis. Amenities available on request include hypo-allergenic bedding.